Dr Lowy asks “Should we be doing something to stimulate B cells?” Dr Topalian showed some data / SEE additional Ab data to be presented @ 8:30AM Tues at WIC session by Dr Zheng /anti-LunX plus Ab can ID T cell target @tylerwhulett /https://t.co/kqNObPUqIS
Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination. https://t.co/ZRJHpI3qFj
RT @BernardAFox: @ChrisHeery @PatelOncology @ad1600 @OncoAlert @JHUPath @JeromeGalon Then look at Gee’s Cell paper/TIL from 2 HLA-A2 pts wi…
No question that T and B cell responses are coordinated. But more precision with T cell measures IMO despite the difficulties. A lot of preexisting antibody resp to shared antigens in cancer so can be challenging to use as a marker/mechanistic insight
RT @BernardAFox: @ChrisHeery @PatelOncology @ad1600 @OncoAlert @JHUPath @JeromeGalon Then look at Gee’s Cell paper/TIL from 2 HLA-A2 pts wi…
@ChrisHeery @00livier @PatelOncology @ad1600 @OncoAlert @JHUPath @JeromeGalon @t_hulett @Nfcanavan @NCI_CCR_SB @myESMO @MDAndersonNews OK! AB responses/protein arrays historically not been robust/But @F_Lund_Johansen is an IgG ROCK STAR & has great tec
RT @BernardAFox: @ChrisHeery @PatelOncology @ad1600 @OncoAlert @JHUPath @JeromeGalon Then look at Gee’s Cell paper/TIL from 2 HLA-A2 pts wi…
RT @ad1600: Wow-super interesting hadn’t appreciated this before. The issue with TMB is also that in high baseline TMB rumors it’s unlikely…
Wow-super interesting hadn’t appreciated this before. The issue with TMB is also that in high baseline TMB rumors it’s unlikely to be useful. When the tumor is heterogeneous with multiple mutagenic pathways it’s more useful.
@ChrisHeery @PatelOncology @ad1600 @OncoAlert @JHUPath @JeromeGalon Then look at Gee’s Cell paper/TIL from 2 HLA-A2 pts with colon cancer use same TCR alpha to see shared colon cancer Ag / https://t.co/dB8iKuQVj4 /Then @t_hulett #FoxLab using “non-biased”
@barlesi @IASLC @Immunopole Lastly/non-biased analyses of IR 2 shared vs nonmutated Ags in preclinical model shows (different) T cells from vac mice can recognize both epitopes https://t.co/z1AICAKJ7q MY OPINION: We have tools 2 figure this out @BMS_ImmunO
*SLIDE SET 2* Dr Stevaux @amgen / #MOA OF #BiTE #immunotherapy Hu/Mu CD3e receptor/need more TIL in tumor to see efficacy/@t_hulett showed his tumor vaccine, currently in clinic trials, incr TIL/ https://t.co/MaoKBiFt7e SHOULD COMBINE? #FoxLab @ChilesResea
@PDRennert @DTUtweet @BMS_ImmunOnc_US @Incyte @MedImmune @UbiVac @ChilesResearch Sorry @PDRennert Dr Steven Rosenberg has published more on shared antigens #MART1 #GP100 neoAgs is like looking for keys under streetlight/WES gives you light/#seromics gives
RT @BernardAFox: Prof Laurence Zitvogel #microbiome Expert @GustaveRoussy talks pleiotropic MOA of #oncomicrobiotics /molecular mimicry for…
RT @BernardAFox: Prof Laurence Zitvogel #microbiome Expert @GustaveRoussy talks pleiotropic MOA of #oncomicrobiotics /molecular mimicry for…
Prof Laurence Zitvogel #microbiome Expert @GustaveRoussy talks pleiotropic MOA of #oncomicrobiotics /molecular mimicry for cancer antigens /something @t_hulett hypothesized to explain preexisting Tu-Rx Ab in tu-naive mice https://t.co/Es1yMZBcJZ #bridge18
RT @BernardAFox: SET 3/#NIBIT18 GREAT TALK by Dr @t_hulett #FoxLab @ChilesResearch #biomarkers of #anticancer response post #cancer #vaccin…
RT @BernardAFox: SET 3/#NIBIT18 GREAT TALK by Dr @t_hulett #FoxLab @ChilesResearch #biomarkers of #anticancer response post #cancer #vaccin…
SET 3/#NIBIT18 GREAT TALK by Dr @t_hulett #FoxLab @ChilesResearch #biomarkers of #anticancer response post #cancer #vaccine/Novel & Important finding #Seromics IDs targets of CTL/https://t.co/Es1yMZBcJZ @NIBITSIENA @parkerici @WICouncil @Asthika @sitc
@KetoCarnivore @HastaVictoriaS1 Did my thesis on overlap between this IgG 'background' and what T cells do: https://t.co/Yi6Gsv9Cqh https://t.co/GsBvOWGcZn
@Crypt0_Donkey @joerogan @YouTube I think the above mentioned 'antibody diversity' closely mirrors the microbes (not yet proven), and is important as a measure of similar 'T cell immunity' (not yet proven). I wrote my PhD thesis on this: https://t.co/Yi6
RT @MaverickNY: Interesting paper from @BernardAFox on antigen-specific T cell repertoire via an antibody surrogate, which has implications…
RT @rbryanbell: Nice work from @ChilesResearch colleagues @BernardAFox, Tyler Huett et al suggesting it is possible to observe antigen-…
RT @MaverickNY: Interesting paper from @BernardAFox on antigen-specific T cell repertoire via an antibody surrogate, which has implications…
RT @MaverickNY: Interesting paper from @BernardAFox on antigen-specific T cell repertoire via an antibody surrogate, which has implications…
RT @MaverickNY: Interesting paper from @BernardAFox on antigen-specific T cell repertoire via an antibody surrogate, which has implications…
RT @rbryanbell: Nice work from @ChilesResearch colleagues @BernardAFox, Tyler Huett et al suggesting it is possible to observe antigen-…
RT @MaverickNY: Interesting paper from @BernardAFox on antigen-specific T cell repertoire via an antibody surrogate, which has implications…
RT @rbryanbell: Nice work from @ChilesResearch colleagues @BernardAFox, Tyler Huett et al suggesting it is possible to observe antigen-…
RT @rbryanbell: Nice work from @ChilesResearch colleagues @BernardAFox, Tyler Huett et al suggesting it is possible to observe antigen-…
RT @rbryanbell: Nice work from @ChilesResearch colleagues @BernardAFox, Tyler Huett et al suggesting it is possible to observe antigen-…
RT @BernardAFox: New approach 2 interpret effect of combo #immunotherapy from Dr @t_hulett #FoxLab @ChilesResearch @ProvHealth /THX @Maveri…
RT @MaverickNY: Interesting paper from @BernardAFox on antigen-specific T cell repertoire via an antibody surrogate, which has implications…
Nice work from @ChilesResearch colleagues @BernardAFox, Tyler Huett et al suggesting it is possible to observe antigen-specific T cell repertoire via antibody surrogate w implications for tumor antigen discovery and clinical monitoring. https://t.co/Iv
RT @MaverickNY: Interesting paper from @BernardAFox on antigen-specific T cell repertoire via an antibody surrogate, which has implications…
RT @MaverickNY: Interesting paper from @BernardAFox on antigen-specific T cell repertoire via an antibody surrogate, which has implications…
RT @MaverickNY: Interesting paper from @BernardAFox on antigen-specific T cell repertoire via an antibody surrogate, which has implications…
New approach 2 interpret effect of combo #immunotherapy from Dr @t_hulett #FoxLab @ChilesResearch @ProvHealth /THX @MaverickNY /Presented @FDAOncology in April/Hope @BMS_ImmunOnc_US @Merck @jsoriamd @DanChenMDPhD @JanssenUS @pfizer @Incyte @Regeneron @merc
RT @MaverickNY: Interesting paper from @BernardAFox on antigen-specific T cell repertoire via an antibody surrogate, which has implications…
Interesting paper from @BernardAFox on antigen-specific T cell repertoire via an antibody surrogate, which has implications for tumor antigen discovery: https://t.co/VLozFza2t3
RT @BernardAFox: BEAUTIFUL DAY IN PORTLAND! Today PHD student/Dr Tyler W Hulett/successfully defended & will graduate @OHSUSOM 4 Innovativ…
RT @BernardAFox: BEAUTIFUL DAY IN PORTLAND! Today PHD student/Dr Tyler W Hulett/successfully defended & will graduate @OHSUSOM 4 Innovativ…
RT @BernardAFox: BEAUTIFUL DAY IN PORTLAND! Today PHD student/Dr Tyler W Hulett/successfully defended & will graduate @OHSUSOM 4 Innovativ…
RT @BernardAFox: BEAUTIFUL DAY IN PORTLAND! Today PHD student/Dr Tyler W Hulett/successfully defended & will graduate @OHSUSOM 4 Innovativ…
BEAUTIFUL DAY IN PORTLAND! Today PHD student/Dr Tyler W Hulett/successfully defended & will graduate @OHSUSOM 4 Innovative #immunotherapy research from #FoxLab @ChilesResearch /https://t.co/Es1yMZjBlp /Jobs?@BMS_ImmunOnc_US @MedImmune @JanssenUS @pfiz
RT @sitcancer: #JITC Research: Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccina…
#JITC Research: Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination https://t.co/CPlayo1QxK https://t.co/9pLGawhdR9
RT @gulleyj1: Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination. Implication…
RT @gulleyj1: Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination. Implication…
RT @rbryanbell: Nice paper from our institute led by @BernardAFox demonstrating method of characterizing antigen and antibody responses to…
RT @rbryanbell: Nice paper from our institute led by @BernardAFox demonstrating method of characterizing antigen and antibody responses to…
RT @sitcancer: #JITC Research: Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccina…
RT @sitcancer: #JITC Research: Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccina…
#JITC Research: Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination https://t.co/fpJqgon6O8 https://t.co/dMvONGcGt8
RT @rbryanbell: Nice paper from our institute led by @BernardAFox demonstrating method of characterizing antigen and antibody responses to…
RT @gulleyj1: Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination. Implication…
RT @rbryanbell: Nice paper from our institute led by @BernardAFox demonstrating method of characterizing antigen and antibody responses to…
RT @rbryanbell: Nice paper from our institute led by @BernardAFox demonstrating method of characterizing antigen and antibody responses to…
RT @gulleyj1: Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination. Implication…
RT @gulleyj1: Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination. Implication…
RT @gulleyj1: Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination. Implication…
RT @gulleyj1: Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination. Implication…
RT @gulleyj1: Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination. Implication…
RT @gulleyj1: Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination. Implication…
Nice paper from our institute led by @BernardAFox demonstrating method of characterizing antigen and antibody responses to cancer vaccine. #FinishCancer @ChilesResearch @OHSUKnight @ProvHealth https://t.co/YFrXZtgL22
Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination. Implications for #Neoantigens and TAA. https://t.co/yJtJfc2a2q #
RT @sitcancer: #JITC Research: Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccina…
RT @sitcancer: #JITC Research: Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccina…
#JITC Research: Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination https://t.co/CPlayo1QxK https://t.co/IV5HNGdwhJ
RT @iskander: Potentially interesting #immunotherapy paper: "Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T…
Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination https://t.co/Aog60iloaP
Potentially interesting #immunotherapy paper: "Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination": https://t.co/MXhjEcMi6B
Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination. https://t.co/AuYuqMgHQ2
RT @sitcancer: New #JITC Research: Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vac…
RT @sitcancer: New #JITC Research: Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vac…
RT @sitcancer: New #JITC Research: Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vac…
New #JITC Research: Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination https://t.co/NvdmFXPnrd https://t.co/VgvkSUGUBA