Biological and Biomedical Applications of Engineered Nucleases

Overview of attention for article published in Molecular Biotechnology, October 2012

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patent: 56 patents

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Summary Patents

So far, Altmetric has seen 56 patents that reference this research output.

High efficiency base editors comprising Gam

Grant US-11932884-B2

United States of America

19 Mar 2024

Nuclease profiling system

Grant US-11920181-B2

United States of America

05 Mar 2024

Methods and compositions for simultaneous editing of both strands of a target double-strand…

Grant US-11912985-B2

United States of America

27 Feb 2024

Suppression of pain by gene editing

Grant US-11898179-B2

United States of America

13 Feb 2024

Editing of CCR2 receptor gene to protect against HIV infection

Grant US-11820969-B2

United States of America

21 Nov 2023

Uses of adenosine base editors

Grant US-11795443-B2

United States of America

24 Oct 2023

Methods and compositions for prime editing nucleotide sequences

Grant US-11795452-B2

United States of America

24 Oct 2023

Methods and compositions for evolving base editors using phage-assisted continuous…

Grant US-11732274-B2

United States of America

22 Aug 2023

Adenosine nucleobase editors and uses thereof

Grant US-11702651-B2

United States of America

18 Jul 2023

Programmable CAS9-recombinase fusion proteins and uses thereof

Grant US-11661590-B2

United States of America

30 May 2023

Methods and compositions for prime editing nucleotide sequences

Grant US-11643652-B2

United States of America

09 May 2023

CAS9 proteins including ligand-dependent inteins

Grant US-11578343-B2

United States of America

14 Feb 2023

Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and…

Grant US-11560566-B2

United States of America

24 Jan 2023

Cytosine to guanine base editor

Grant US-11542496-B2

United States of America

03 Jan 2023

Incorporation of unnatural amino acids into proteins using base editing

Grant US-11542509-B2

United States of America

03 Jan 2023

Methods and compositions for prime editing nucleotide sequences

Grant US-11447770-B1

United States of America

20 Sep 2022

CRISPR-related methods and compositions with governing gRNAS

Grant US-11390887-B2

United States of America

19 Jul 2022

High efficiency base editors comprising Gam

Grant US-11319532-B2

United States of America

03 May 2022

AAV delivery of nucleobase editors

Grant US-11306324-B2

United States of America

19 Apr 2022

Switchable CAS9 nucleases and uses thereof

Grant US-11299755-B2

United States of America

12 Apr 2022

Nucleobase editors comprising nucleic acid programmable DNA binding proteins

Grant US-11268082-B2

United States of America

08 Mar 2022

Nucleobase editors and uses thereof

Grant US-11214780-B2

United States of America

04 Jan 2022

Cas variants for gene editing

Grant US-11124782-B2

United States of America

21 Sep 2021

Fusions of Cas9 domains and nucleic acid-editing domains

Grant US-11053481-B2

United States of America

06 Jul 2021

Engineered transcription activator-like effector (TALE) domains and uses thereof

Grant US-11046948-B2

United States of America

29 Jun 2021

Nuclease profiling system

Grant US-10954548-B2

United States of America

23 Mar 2021

Adenosine nucleobase editors and uses thereof

Grant US-10947530-B2

United States of America

16 Mar 2021

Delivery of negatively charged proteins using cationic lipids

Grant US-10912833-B2

United States of America

09 Feb 2021

CAS9 variants and uses thereof

Grant US-10858639-B2

United States of America

08 Dec 2020

Editing of CCR5 receptor gene to protect against HIV infection

Grant US-10745677-B2

United States of America

18 Aug 2020

CAS9 proteins including ligand-dependent inteins

Grant US-10704062-B2

United States of America

07 Jul 2020

Delivery system for functional nucleases

Grant US-10682410-B2

United States of America

16 Jun 2020

CRISPR-related methods and compositions with governing gRNAs

Grant US-10640788-B2

United States of America

05 May 2020

Switchable Cas9 nucleases and uses thereof

Grant US-10597679-B2

United States of America

24 Mar 2020

Methods for identifying a target site of a CAS9 nuclease

Grant US-10508298-B2

United States of America

17 Dec 2019

Cas variants for gene editing

Grant US-10465176-B2

United States of America

05 Nov 2019

Evaluation and improvement of nuclease cleavage specificity

Grant US-10323236-B2

United States of America

18 Jun 2019

Engineered transcription activator-like effector (TALE) domains and uses thereof

Application US-10227581-B2

United States of America

12 Mar 2019

CRISPR-related methods and compositions with governing gRNAS

Grant US-10190137-B2

United States of America

29 Jan 2019

Nucleobase editors and uses thereof

Grant US-10167457-B2

United States of America

01 Jan 2019

Adenosine nucleobase editors and uses thereof

Grant US-10113163-B2

United States of America

30 Oct 2018

CAS9 proteins including ligand-dependent inteins

Grant US-10077453-B2

United States of America

18 Sep 2018

Delivery of negatively charged proteins using cationic lipids

Grant US-9999671-B2

United States of America

19 Jun 2018

Methods for nucleic acid editing

Grant US-9840699-B2

United States of America

12 Dec 2017

CRISPR-related methods and compositions with governing gRNAS

Grant US-9834791-B2

United States of America

05 Dec 2017

Use of cationic lipids to deliver CAS9

Grant US-9737604-B2

United States of America

22 Aug 2017

Delivery system for functional nucleases

Grant US-9526784-B2

United States of America

27 Dec 2016

Cas9-recombinase fusion proteins and uses thereof

Grant US-9388430-B2

United States of America

12 Jul 2016