Stability of Protein Pharmaceuticals: An Update

Overview of attention for article published in Pharmaceutical Research, February 2010

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In the top 25% of all research outputs scored by Altmetric
High Attention Score compared to outputs of the same age (94th percentile)
High Attention Score compared to outputs of the same age and source (89th percentile)

Mentioned by

news: 1 news outlet

patent: 83 patents

Citations

dimensions_citation: 903 Dimensions

Readers on

mendeley: 1258 Mendeley
citeulike: 1 CiteULike
connotea: 1 Connotea

Summary News Patents Dimensions citations

So far, Altmetric has seen 83 patents that reference this research output.

Ultra-pure agonists of guanylate cyclase C, method of making and using same

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United States of America

Method of treating prostate cancer with GnRH antagonist

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United States of America

Releasable conjugates

Grant US-11786599-B2

United States of America

Method of treating prostate cancer with GnRH antagonist

Grant US-11766468-B2

United States of America

Liquid pharmaceutical composition

Grant US-11752209-B2

United States of America

Liquid pharmaceutical composition

Grant US-11752208-B2

United States of America

Liquid pharmaceutical composition

Grant US-11712471-B2

United States of America

Liquid pharmaceutical composition

Grant US-11707524-B2

United States of America

Formulations with reduced oxidation

Grant US-11596620-B2

United States of America

Pharmaceutical formulations of C1 esterase inhibitor

Grant US-11554156-B2

United States of America

Manufacture of degarelix

Grant US-11510962-B2

United States of America

A DRUG FORMULATION FOR USE IN THE EFFECTIVE CONTROL OF ACUTE AND/OR CHRONIC PAIN

Grant EP-3442557-B1

European Patent Office

Releasable GLP-1 conjugates

Grant US-11357828-B2

United States of America

Renal-homing peptide conjugates and methods of use thereof

Grant US-11331393-B2

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Manufacture of Degarelix

Grant US-11260102-B2

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Vasopressin formulations for use in treatment of hypotension

Grant US-11207372-B2

United States of America

Vasopressin formulations for use in treatment of hypotension

Grant US-11135265-B2

United States of America

Bifunctional compounds

Grant US-11130794-B2

United States of America

NERVE GROWTH FACTOR COMPOSITION AND INJECTION POWDER

Grant EP-3287139-B1

European Patent Office

RAPID-ACTING INSULIN COMPOSITIONS

Application US-20210169988-A1

United States of America

Liver-type fatty acid-binding protein standard, method for evaluating standard, method…

Grant US-10981960-B2

United States of America

Methods of treating prostate cancer with GnRH antagonist

Grant US-10973870-B2

United States of America

Antibody formulations

Grant US-10947307-B2

United States of America

Connexin 43 antibodies and uses thereof

Application CN-112368299-A

China

Anti-BAFFR antibody formulations and methods of use thereof

Grant US-10899841-B2

United States of America

EGF(A) analogues with fatty acid substituents

Grant US-10822385-B2

United States of America

Manufacture of Degarelix

Grant US-10765721-B2

United States of America

Methods of treating prostate cancer with GnRH antagonist

Grant US-10729739-B2

United States of America

Method of treating prostate cancer with GnRH antagonist

Grant US-10695398-B2

United States of America

Formulations with reduced oxidation

Grant US-10653779-B2

United States of America

RELEASABLE ANTIBODY CONJUGATES

Application WO-2019171358-A1

World Intellectual Property Organisation (WIPO)

Methods of treating chronic inflammatory diseases

Grant US-10213482-B2

United States of America

Manufacture of Degarelix

Grant US-10172906-B2

United States of America

Pharmaceutical preparation

Application JP-2018162295-A

Japan

Pharmaceutical formulations of TNF-alpha antibodies

Application US-10093728-B2

United States of America

Protein purification methods to reduce acidic species

Grant US-9957318-B2

United States of America

LIVER-TYPE FATTY ACID-BINDING PROTEIN PREPARATION, METHOD FOR EVALUATING PREPARATION…

Application WO-2017217514-A1

World Intellectual Property Organisation (WIPO)

MODIFIED PEPTIDES AND THEIR USE FOR TREATING AUTOIMMUNE DISEASES

Application EP-3202413-A1

European Patent Office

Liver-type fatty acid binding protein preparation, method for evaluating the preparation…

Application JP-6174778-B1

Japan

Methods to modulate lysine variant distribution

Grant US-9708400-B2

United States of America

Protein purification using displacement chromatography

Grant US-9708399-B2

United States of America

Low acidic species compositions and methods for producing and using the same using…

Grant US-9688752-B2

United States of America

Cell culture methods to reduce acidic species

Grant US-9683033-B2

United States of America

Modified peptides and their use for treating autoimmune diseases

Grant US-9657072-B2

United States of America

Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins

Grant US-9598667-B2

United States of America

PHARMACEUTICAL PREPARATION

Application JP-2017019855-A

Japan

Glycoengineered binding protein compositions

Grant US-9550826-B2

United States of America

Low acidic species compositions and methods for producing and using the same

Grant US-9522953-B2

United States of America

Methods to control protein heterogeneity

Grant US-9512214-B2

United States of America

Human antibodies that bind human TNF-alpha and methods of preparing the same

Grant US-9505833-B2

United States of America

Methods for controlling the galactosylation profile of recombinantly-expressed proteins

Grant US-9505834-B2

United States of America

Methods for modulating protein glycosylation profiles of recombinant protein therapeutics…

Grant US-9499614-B2

United States of America

Modulated lysine variant species compositions and methods for producing and using the same

Grant US-9499616-B2

United States of America

Anti-BAFFR antibody formulations

Application US-9458240-B2

United States of America

Cell culture media and methods of antibody production

Grant US-9441035-B2

United States of America

Methods for controlling the galactosylation profile of recombinantly-expressed proteins

Grant US-9365645-B1

United States of America

Cell culture methods to reduce acidic species

Grant US-9359434-B2

United States of America

Protein purification methods to reduce acidic species

Grant US-9346879-B2

United States of America

Low acidic species compositions

Grant US-9334319-B2

United States of America

Low acidic species compositions and methods for producing and using the same

Grant US-9315574-B2

United States of America

Methods to control protein heterogeneity

Grant US-9290568-B2

United States of America

Low acidic species compositions and methods for producing and using the same

Grant US-9266949-B2

United States of America

Methods for controlling the galactosylation profile of recombinantly-expressed proteins

Grant US-9255143-B2

United States of America

Purification of antibodies using hydrophobic interaction chromatography

Grant US-9249182-B2

United States of America

Methods to control protein heterogeneity

Grant US-9234033-B2

United States of America

Methods to control protein heterogeneity

Grant US-9206390-B2

United States of America

Low acidic species compositions and methods for producing and using the same

Grant US-9200070-B2

United States of America

Low acidic species compositions and methods for producing and using the same

Grant US-9200069-B2

United States of America

Human antibodies that bind human TNF-alpha and methods of preparing the same

Grant US-9193787-B2

United States of America

Methods to modulate lysine variant distribution

Grant US-9181572-B2

United States of America

Modulated lysine variant species compositions and methods for producing and using the same

Grant US-9181337-B2

United States of America

Cell culture methods to reduce acidic species

Grant US-9150645-B2

United States of America

Methods for controlling the galactosylation profile of recombinantly-expressed proteins

Grant US-9090688-B2

United States of America

Protein purification using displacement chromatography

Grant US-9067990-B2

United States of America

Methods for controlling the galactosylation profile of recombinantly-expressed proteins

Grant US-9062106-B2

United States of America

Formulations of growth hormone releasing factor (GRF) molecules with improved stability

Grant US-8871713-B2

United States of America

FORMULATIONS WITH REDUCED OXIDATION

Application WO-2014160497-A1

World Intellectual Property Organisation (WIPO)

FORMULATIONS WITH REDUCED OXIDATION

Application WO-2014160495-A1

World Intellectual Property Organisation (WIPO)

Macromolecule transduction domains and methods for identification and uses thereof

Application US-8629097-B2

United States of America

PHARMACEUTICAL FORMULATIONS OF TNF-ALPHA ANTIBODIES

Application WO-2013164837-A1

World Intellectual Property Organisation (WIPO)

MODIFIED PEPTIDES AND THEIR USE FOR TREATING AUTOIMMUNE DISEASES

Application WO-2013088194-A1

World Intellectual Property Organisation (WIPO)

ANTIBODY FORMULATION

Application WO-2012076670-A3

World Intellectual Property Organisation (WIPO)

NOVEL MACROMOLECULE TRANSDUCTION DOMAINS AND METHODS FOR IDENTIFICATION AND USES THEREOF

Application US-20100197598-A1

United States of America