RT @olopeznu: 10/ Answer is C - This fusion is detected in almost all well-characterized MCs whereas absent in other subtypes of chondrosar…
👉 HEY1 is downstream of the Notch pathway 👉 HEY1-NCOA2 fusion promote sarcomagenesis by multiple mechanisms, including direct DNA binding, protein-protein interaction, and epigenetic modification A nice recent review on the biology of this fusion: https:
RT @zucchiatti_: #pedipath great case 💥
RT @olopeznu: 10/ Answer is C - This fusion is detected in almost all well-characterized MCs whereas absent in other subtypes of chondrosar…
#pedipath great case 💥
RT @olopeznu: 10/ Answer is C - This fusion is detected in almost all well-characterized MCs whereas absent in other subtypes of chondrosar…
10/ Answer is C - This fusion is detected in almost all well-characterized MCs whereas absent in other subtypes of chondrosarcomas. The consistent molecular detection of the HEY1-NCOA2 fusion establishes it as a defining molecular diagnostic marker 👉🏼https
RT @VivekSubbiah: @Annika_poresfi @bvantine1 @immunosarc @Sarcoma_QB @ShirajSenMDPhD @APConley77 @jalivingston_md Review on mesenchymal cho…
@Annika_poresfi @bvantine1 @immunosarc @Sarcoma_QB @ShirajSenMDPhD @APConley77 @jalivingston_md Review on mesenchymal chondrosrcoma @APConley77 @JasonRoszik @jalivingston_md @DrValeraeLewis https://t.co/LeYyrq3Mrk
Mesenchymal Chondrosarcoma: a Review with Emphasis on its Fusion-Driven Biology. https://t.co/LZcwQfPgn1
Pubmed: Mesenchymal Chondrosarcoma: a Review with Emphasis on its Fusion-Driven Biology. https://t.co/jp2whzCrue