Method for the treatment of mucopolysaccharidosis type I Grant US-11857641-B2 United States of America 02 Jan 2024
Gene therapy for treating Mucopolysaccharidosis type II Grant US-11819539-B2 United States of America 21 Nov 2023
Methods and compositions for increasing alpha-L-iduronidase activity in the CNS Grant US-11512145-B2 United States of America 29 Nov 2022
Gene therapy for treating mucopolysaccharidosis type II Grant US-11253612-B2 United States of America 22 Feb 2022
Macromolecular compositions that cross the blood-brain barrier and methods of use thereof Grant US-11155631-B2 United States of America 26 Oct 2021
Methods and compositions for increasing iduronate 2-sulfatase activity in the CNS Grant US-11028156-B2 United States of America 08 Jun 2021
Structure, manufacturing and uses of human-derived cell-permeable peptides conjugated… Grant US-10947539-B2 United States of America 16 Mar 2021
Adenoassociated virus vectors for the treatment of mucopolysaccharidoses Grant US-10617771-B2 United States of America 14 Apr 2020
Methods and compositions for increasing N-acetylglucosaminidase (NAGLU) activity in the… Grant US-10538589-B2 United States of America 21 Jan 2020
FUSION PROTEINS COMPRISING HOXD12 AND NEMO BINDING DOMAIN AND THEIR USE Application EP-3581207-A1 European Patent Office 18 Dec 2019
METHODS AND COMPOSITIONS FOR INCREASING IDURONATE 2-SULFATASE ACTIVITY IN THE CNS Application EP-3533467-A2 European Patent Office 04 Sep 2019
Structure, manufacturing and uses of human-derived cell-permeable peptides conjugated… Grant US-10301629-B2 United States of America 28 May 2019
Methods and compositions for increasing α-L-iduronidase activity in the CNS Grant US-10202467-B2 United States of America 12 Feb 2019
Macromolecular compositions that cross the blood-brain barrier and methods of use thereof Grant US-10144783-B2 United States of America 04 Dec 2018
Methods and compositions for increasing iduronate 2-sulfatase activity in the CNS Grant US-10011651-B2 United States of America 03 Jul 2018
Methods and compositions for increasing arylsulfatase A activity in the CNS Grant US-9975955-B2 United States of America 22 May 2018
Methods and compositions for increasing α-L-iduronidase activity in the CNS Grant US-9567400-B2 United States of America 14 Feb 2017
Compositions and methods for blood-brain barrier delivery of IgG-decoy receptor fusion… Grant US-9533055-B2 United States of America 03 Jan 2017
Methods and compositions for increasing α-L-iduronidase activity in the CNS Grant US-8974791-B2 United States of America 10 Mar 2015
Methods and compositions for increasing arylsulfatase A activity in the CNS Grant US-8920801-B2 United States of America 30 Dec 2014
Methods and compositions for increasing iduronate 2-sulfatase activity in the CNS Grant US-8834874-B2 United States of America 16 Sep 2014
Genetically encoded multifunctional compositions bidirectionally transported between… Grant US-8759297-B2 United States of America 24 Jun 2014
Methods for diagnosing CNS disorders with fusion antibodies that cross the blood-brain… Grant US-8753610-B2 United States of America 17 Jun 2014
Fusion proteins for delivery of GDNF to the CNS Grant US-8741260-B2 United States of America 03 Jun 2014
Methods and compositions for increasing arylsulfatase A activity in the CNS Grant US-8715661-B2 United States of America 06 May 2014
Methods of lysosomal storage disease therapy Grant US-8679478-B2 United States of America 25 Mar 2014
Methods for diagnosing and treating CNS disorders by trans-blood-brain barrier delivery… Grant US-8497246-B2 United States of America 30 Jul 2013
ANTI-TNF- THERAPY FOR THE MUCOPOLYSACCHARIDOSES AND OTHER LYSOSOMAL DISORDERS Application WO-2012177778-A1 World Intellectual Property Organisation (WIPO) 27 Dec 2012
METHODS AND COMPOSITIONS FOR INCREASING IDURONATE 2-SULFATASE ACTIVITY IN THE CNS Application WO-2011044542-A1 World Intellectual Property Organisation (WIPO) 14 Apr 2011