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Influenza vaccines: recent advances in production technologies

Overview of attention for article published in Applied Microbiology & Biotechnology, January 2005
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

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5 patents
wikipedia
2 Wikipedia pages

Citations

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50 Dimensions

Readers on

mendeley
60 Mendeley
Title
Influenza vaccines: recent advances in production technologies
Published in
Applied Microbiology & Biotechnology, January 2005
DOI 10.1007/s00253-004-1874-1
Pubmed ID
Authors

N. Bardiya, J. H. Bae

Abstract

In spite of ongoing annual vaccination programs, the seasonal influenza epidemics remain a major cause of high morbidity and mortality. The currently used "inactivated" vaccines provide very short-term and highly specific humoral immunity due to the frequent antigenic variations in the influenza virion. These intra-muscularly administered vaccines also fail to induce protective mucosal immunity at the portal of viral entry and destruction of the virally infected cells by induction of cytotoxic T lymphocytes. Therefore, it is necessary to develop immunologically superior vaccines. This article highlights some of the recent developments in investigational influenza vaccines. The most notable recent developments of interest include the use of immunopotentiators, development of DNA vaccines, use of reverse genetics, and the feasibility of mammalian cell-based production processes. Presently, due to their safety and efficacy, the cold-adapted "live attenuated" vaccines are seen as viable alternatives to the "inactivated vaccines". The DNA vaccines are gaining importance due to the induction of broad-spectrum immunity. In addition, recent advances in recombinant technologies have shown the possibility of constructing pre-made libraries of vaccine strains, so that adequately preparations can be made for epidemics and pandemics.

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 2%
New Zealand 1 2%
Singapore 1 2%
Unknown 57 95%

Demographic breakdown

Readers by professional status Count As %
Student > Master 12 20%
Student > Bachelor 11 18%
Researcher 11 18%
Student > Ph. D. Student 10 17%
Unspecified 3 5%
Other 13 22%
Readers by discipline Count As %
Agricultural and Biological Sciences 24 40%
Medicine and Dentistry 11 18%
Engineering 10 17%
Immunology and Microbiology 4 7%
Unspecified 3 5%
Other 8 13%

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 May 2014.
All research outputs
#1,747,153
of 10,673,460 outputs
Outputs from Applied Microbiology & Biotechnology
#341
of 4,104 outputs
Outputs of similar age
#49,906
of 249,729 outputs
Outputs of similar age from Applied Microbiology & Biotechnology
#10
of 129 outputs
Altmetric has tracked 10,673,460 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,104 research outputs from this source. They receive a mean Attention Score of 3.0. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 249,729 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 129 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.