Treatment with opioid antagonists and mTOR inhibitors Grant US-10383869-B2 United States of America 20 Aug 2019
Stable pharmaceutical formulations of methylnaltrexone Grant US-10376584-B2 United States of America 13 Aug 2019
Crystal forms of (R)-N-methylnaltrexone bromide and uses thereof Grant US-9879024-B2 United States of America 30 Jan 2018
Peripheral opioid receptor antagonists and uses thereof Grant US-9724343-B2 United States of America 08 Aug 2017
Use of opioid antagonists to attenuate endothelial cell proliferation and migration Grant US-9675602-B2 United States of America 13 Jun 2017
Stable pharmaceutical formulations of methylnaltrexone Grant US-9669096-B2 United States of America 06 Jun 2017
Use of opioid antagonists to attenuate endothelial cell proliferation and migration Grant US-9662325-B2 United States of America 30 May 2017
Use of opioid antagonists to attenuate endothelial cell proliferation and migration Grant US-9662390-B2 United States of America 30 May 2017
Treatment with opioid antagonists and mTOR inhibitors Grant US-9526723-B2 United States of America 27 Dec 2016
Peripheral opioid receptor antagonists and uses thereof Grant US-9492445-B2 United States of America 15 Nov 2016
Peripheral opioid receptor antagonists and uses thereof Grant US-9180125-B2 United States of America 10 Nov 2015
Crystal forms of (R)-N-methylnaltrexone bromide and uses thereof Grant US-9102680-B2 United States of America 11 Aug 2015
Methods of preventing and treating gastrointestinal dysfunction Grant US-8946262-B2 United States of America 03 Feb 2015
Preparation and use of (R),(R)-2,2′-bis-methylnaltrexone Grant US-8916706-B2 United States of America 23 Dec 2014
Peripheral opioid receptor antagonists and uses thereof Grant US-8853232-B2 United States of America 07 Oct 2014
Peripheral opioid receptor antagonists and uses thereof Grant US-8822490-B2 United States of America 02 Sep 2014
Peripheral opioid receptor antagonists and uses thereof Grant US-8772310-B2 United States of America 08 Jul 2014
Treatment with opioid antagonists and mTOR inhibitors Grant US-8685995-B2 United States of America 01 Apr 2014
Peripheral opioid receptor antagonists and uses thereof Grant US-8546418-B2 United States of America 01 Oct 2013
Use of opioid antagonists to attenuate endothelial cell proliferation and migration Grant US-8524731-B2 United States of America 03 Sep 2013
Preparation and use of (R),(R)-2,2′-bis-methylnaltrexone Grant US-8471022-B2 United States of America 25 Jun 2013
Peripheral opioid receptor antagonists and uses thereof Grant US-8455644-B2 United States of America 04 Jun 2013
Peripheral opioid receptor antagonists and uses thereof Grant US-8420663-B2 United States of America 16 Apr 2013
Substituted piperidine compounds and methods of their use Application US-8404693-B2 United States of America 26 Mar 2013
Hexahydro-cycloheptapyrazole cannabinoid modulators Grant US-8378117-B2 United States of America 19 Feb 2013
Hexahydro-cycloheptapyrazole cannabinoid modulators Grant US-8378096-B2 United States of America 19 Feb 2013
Peripheral opioid receptor antagonists and uses thereof Grant US-8338446-B2 United States of America 25 Dec 2012
Peripheral opioid receptor antagonists and uses thereof Grant US-8247425-B2 United States of America 21 Aug 2012
Spirocyclic heterocyclic derivatives and methods of their use Grant US-8071611-B2 United States of America 06 Dec 2011
Spirocyclic heterocyclic derivatives and methods of their use Grant US-8022060-B2 United States of America 20 Sep 2011
Spirocyclic heterocyclic derivatives and methods of their use Grant US-7906646-B2 United States of America 15 Mar 2011
Substituted piperidine compounds and methods of their use Application US-7884102-B2 United States of America 08 Feb 2011
Hexahydro-cyclooctyl pyrazole cannabinoid modulators Grant US-7851498-B2 United States of America 14 Dec 2010
Hexahydro-cyclooctyl pyrazole cannabinoid modulators Grant US-7825151-B2 United States of America 02 Nov 2010
Substituted piperidine compounds and methods of their use Application US-7820827-B2 United States of America 26 Oct 2010
Substituted piperidine compounds and methods of their use Application US-7767814-B2 United States of America 03 Aug 2010
Methods for the treatment or inhibition of ileus Grant US-7696220-B2 United States of America 13 Apr 2010
Spirocyclic heterocyclic derivatives and methods of their use Grant US-7638527-B2 United States of America 29 Dec 2009
Spirocyclic heterocyclic derivatives and methods of their use Grant US-7598261-B2 United States of America 06 Oct 2009
Spirocyclic heterocyclic derivatives and methods of their use Grant US-7576207-B2 United States of America 18 Aug 2009
Spirocyclic heterocyclic derivatives and methods of their use Grant US-7338962-B2 United States of America 04 Mar 2008
Processes for the preparation of peripheral opioid antagonist compounds and intermediates… Application US-7091354-B2 United States of America 15 Aug 2006
Substituted piperidine compounds and methods of their use Application US-7087749-B2 United States of America 08 Aug 2006
Substituted piperidine compounds and methods of their use Application US-6992090-B2 United States of America 31 Jan 2006
Processes for the preparation of peripheral opioid antagonist compounds and intermediates… Application US-6794510-B2 United States of America 21 Sep 2004
Methods for the treatment and prevention of ileus Grant US-6469030-B2 United States of America 22 Oct 2002
Methods and compositions involving opioids and antagonists thereof Grant US-6451806-B2 United States of America 17 Sep 2002
Use of fedotozine in the treatment of functional states of intestinal obstructions Grant US-5362756-A United States of America 08 Nov 1994