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Biotransformation of mulberroside A from Morus alba results in enhancement of tyrosinase inhibition

Overview of attention for article published in Journal of Industrial Microbiology & Biotechnology, April 2010
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#24 of 956)
  • High Attention Score compared to outputs of the same age (85th percentile)
  • High Attention Score compared to outputs of the same age and source (94th percentile)

Mentioned by

patent
2 patents
wikipedia
4 Wikipedia pages

Citations

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28 Dimensions

Readers on

mendeley
35 Mendeley
Title
Biotransformation of mulberroside A from Morus alba results in enhancement of tyrosinase inhibition
Published in
Journal of Industrial Microbiology & Biotechnology, April 2010
DOI 10.1007/s10295-010-0722-9
Pubmed ID
Authors

Jeong-Keun Kim, Mijin Kim, Ssang-Goo Cho, Myung-Kyoo Kim, Suhng Wook Kim, Young-Hee Lim

Abstract

Mulberroside A, a glycosylated stilbene, was isolated and identified from the ethanol extract of the roots of Morus alba. Oxyresveratrol, the aglycone of mulberroside A, was produced by enzymatic hydrolysis of mulberroside A using the commercial enzyme Pectinex. Mulberroside A and oxyresveratrol showed inhibitory activity against mushroom tyrosinase with an IC(50) of 53.6 and 0.49 microM, respectively. The tyrosinase inhibitory activity of oxyresveratrol was thus approximately 110-fold higher than that of mulberroside A. Inhibition kinetics showed mulberroside A to be a competitive inhibitor of mushroom tyrosinase with L-tyrosine and L-DOPA as substrate. Oxyresveratrol showed mixed inhibition and noncompetitive inhibition against L-tyrosine and L-DOPA, respectively, as substrate. The results indicate that the tyrosinase inhibitory activity of mulberroside A was greatly enhanced by the bioconversion process.

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Indonesia 1 3%
Malaysia 1 3%
Unknown 33 94%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 17%
Researcher 6 17%
Student > Ph. D. Student 5 14%
Student > Postgraduate 5 14%
Student > Doctoral Student 4 11%
Other 9 26%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 49%
Unspecified 5 14%
Chemistry 4 11%
Medicine and Dentistry 3 9%
Immunology and Microbiology 2 6%
Other 4 11%

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 August 2017.
All research outputs
#1,480,902
of 12,503,594 outputs
Outputs from Journal of Industrial Microbiology & Biotechnology
#24
of 956 outputs
Outputs of similar age
#37,952
of 270,695 outputs
Outputs of similar age from Journal of Industrial Microbiology & Biotechnology
#2
of 34 outputs
Altmetric has tracked 12,503,594 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 956 research outputs from this source. They receive a mean Attention Score of 3.6. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 270,695 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.