Promoter methylation status of hMLH1, hMSH2, and MGMT genes in colorectal cancer associated with adenoma–carcinoma sequence

Καρκινογένεση

Tumor

Un tumor es cualquier alteración de los tejidos que produzca un aumento de volumen. Es un agrandamiento anormal de una parte del cuerpo que aparece, por lo tanto…

신생물

신생물은 조직의 비정상적이고 과도한 성장의 한 유형이다. 신생물이 형성되거나 생성되는 과정을 신생물 형성(neoplasia)이라고 한다. 신생물의 성장은 주변 정상 조직의 성장과 달리 통제되지 않으며, 원래의 유발 요인이 제거되더라도 비정상적으로 계속 성장할 수 있다.

Metilación del ADN en el cáncer

La metilación del ADN en el cáncer desempeña una variedad de funciones, ayudando a cambiar las células sanas mediante la regulación de la expresión génica a un patrón de…

O6-メチルグアニン-DNAメチルトランスフェラーゼ

O6-メチルグアニン-DNAメチルトランスフェラーゼ（、略称: MGMT）またはO6-アルキルグアニン-DNAアルキルトランスフェラーゼ（、略称: AGT、AGAT）は、ヒトではMGMT遺伝子にコードされるタンパク質である.

MSH2

MSH2（mutS homolog 2）は、ヒトではに位置するMSH2遺伝子にコードされるタンパク質である. MSH2はがん抑制遺伝子であり、より具体的にはDNAミスマッチ修復（MMR）タンパク質MSH2をコードするである.

MSH2

الوراثة اللاجينية للسرطان

Neoplasm

Un neoplasm este un tip de creștere anormală și excesivă, numită neoplazie, a unui țesut.

เนื้องอก

DNA methylation in cancer

All mammalian cells descended from a fertilized egg (a zygote) share a common DNA sequence (except for new mutations in some lineages).

MSH2

DNA mismatch repair protein Msh2 also known as MutS protein homolog 2 or MSH2 is a protein that in humans is encoded by the MSH2 gene, which is located on chromosome 2.

O-6-methylguanine-DNA methyltransferase

O6-alkylguanine DNA alkyltransferase (also known as AGT, MGMT or AGAT) is a protein that in humans is encoded by the O6-methylguanine DNA methyltransferase (MGMT) gene.

بازسازی دی‌ان‌ای

DNA repair

DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome.

Field cancerization

Field cancerization (also termed field change, field change cancerization, field carcinogenesis, cancer field effect or premalignant field defect) is a biological…

Cancer epigenetics

Cancer epigenetics is the study of epigenetic modifications to the genome of cancer cells that do not involve a change in the nucleotide sequence.

Carcinogenesis

Carcinogenesis or oncogenesis or tumorigenesis is the formation of a cancer, whereby normal cells are transformed into cancer cells.

Neoplasm

Neoplasm (from Ancient Greek νεο- neo- "new" and πλάσμα plasma "formation, creation"), also commonly referred to as a tumor or tumour, is an abnormal growth of tissue.