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NS 1 lasts longer than the dengue virus nucleic acid in the clinically suspected patients with dengue fever and dengue haemorrhagic fever

Overview of attention for article published in VirusDisease, September 2017
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Title
NS 1 lasts longer than the dengue virus nucleic acid in the clinically suspected patients with dengue fever and dengue haemorrhagic fever
Published in
VirusDisease, September 2017
DOI 10.1007/s13337-017-0401-9
Pubmed ID
Authors

Nadeera Sirisena, Faseeha Noordeen, LakKumar Fernando

Abstract

The objectives of the study were to compare the DENV NS1 and nucleic acid positivity in dengue fever (DF) and dengue haemorrhagic fever (DHF) patients and to evaluate the usefulness of these parameters in severe dengue. Blood samples were collected from 91 patients with DF or DHF (fever days 3-9) from Gampaha and Negombo General Hospitals, Sri Lanka and tested for DENV NS1 antigen and nucleic acid. On fever day 3, 67% of the DF and 33% of the DHF patients had DENV nucleic acid whereas 50% of the DF and 67% of the DHF patients had NS1. On fever day 4, 67% of the DF and 100% of the DHF patients had DENV nucleic acid whereas 83% of the DF and DHF patients had NS1. From fever day 5 in the DHF group, DENV nucleic acid declined but NS1 remained detectable even on day 9 (p < 0.0001). NS1 positivity did not correlate with the decrease in the WBC count in DF and DHF patients (p > 0.05) whereas NS1 positivity significantly correlated with the decrease in the platelet count in DF and DHF patients (p < 0.0001). NS1 is a useful marker to detect DENV infection even in the latter stages of DHF.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 7 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 7 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 43%
Unspecified 2 29%
Student > Doctoral Student 1 14%
Student > Postgraduate 1 14%
Readers by discipline Count As %
Unspecified 4 57%
Chemical Engineering 1 14%
Immunology and Microbiology 1 14%
Medicine and Dentistry 1 14%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 January 2018.
All research outputs
#10,963,106
of 12,371,547 outputs
Outputs from VirusDisease
#76
of 144 outputs
Outputs of similar age
#291,383
of 350,345 outputs
Outputs of similar age from VirusDisease
#8
of 13 outputs
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So far Altmetric has tracked 144 research outputs from this source. They receive a mean Attention Score of 0.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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