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Modified Natural Clinoptilolite Detoxifies Small Mammal’s Organism Loaded with Lead II: Genetic, Cell, and Physiological Effects

Overview of attention for article published in Biological Trace Element Research, December 2011
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (53rd percentile)
  • Good Attention Score compared to outputs of the same age and source (76th percentile)

Mentioned by

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2 tweeters
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3 Facebook pages

Citations

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8 Dimensions

Readers on

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14 Mendeley
Title
Modified Natural Clinoptilolite Detoxifies Small Mammal’s Organism Loaded with Lead II: Genetic, Cell, and Physiological Effects
Published in
Biological Trace Element Research, December 2011
DOI 10.1007/s12011-011-9289-1
Pubmed ID
Authors

Margarita Topashka-Ancheva, Michaela Beltcheva, Roumiana Metcheva, J. Antonio Heredia Rojas, Abraham O. Rodriguez-De la Fuente, Tsvetelina Gerasimova, Laura E. Rodríguez-Flores, Svetla E. Teodorova

Abstract

The detoxification capacity of the clinoptilolite modification KLS-10-MA used as food additive in small mammals, chronically lead-exposed, was proven for the first time. The modified clinoptilolite was prepared based on natural Bulgarian clinoptilolite deposits. As a powder, it was mechanically mixed at 12.5% concentration with the conventional forage for small rodents. Lead in the form of aqueous solution of Pb(NO(3))(2) was diluted in the drinking water. In the ecotoxicological experiment covering 90 days, imprinting control region laboratory mice were used. They were allocated into four groups: group 1, (control): animals fed with conventional food for small rodents and water; group 2: animals fed with conventional food + clinosorbent KLS-10-MA and water; group 3: animals fed with conventional food and water + Pb(NO(3))(2); and group 4: animals fed with conventional food + KLS-10-MA and water + Pb(NO(3))(2). A group of non-exposed healthy animals was fed with conventional forage mixed with KLS-10-MA to prove eventual toxicity of the sorbent and influence on growth performance. The changes in the chromosome structure, mitotic index, erythrocyte form, erythropoiesis, and body weight gain were recorded. On day 90, the following relations were established: Pb-exposed and clinoptilolite-supplemented mice exhibited 2.3-fold lower chromosome aberrations frequency, 2.5-fold higher mitotic index, and 1.5-fold higher percentage normal erythrocytes 1.3-fold higher body weight compared to Pb-exposed and unsupplemented animals. The obtained data showed that the sorbent is practically non-toxic. The results of the present study encourage a further elaboration of a reliable drug based on the tested substance in the cases of chronic lead intoxication.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 7%
Nigeria 1 7%
Unknown 12 86%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 21%
Student > Bachelor 2 14%
Student > Ph. D. Student 2 14%
Professor > Associate Professor 2 14%
Student > Doctoral Student 1 7%
Other 2 14%
Unknown 2 14%
Readers by discipline Count As %
Nursing and Health Professions 3 21%
Medicine and Dentistry 3 21%
Agricultural and Biological Sciences 2 14%
Economics, Econometrics and Finance 1 7%
Social Sciences 1 7%
Other 1 7%
Unknown 3 21%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 July 2017.
All research outputs
#6,552,660
of 11,437,561 outputs
Outputs from Biological Trace Element Research
#627
of 1,165 outputs
Outputs of similar age
#109,815
of 251,810 outputs
Outputs of similar age from Biological Trace Element Research
#5
of 26 outputs
Altmetric has tracked 11,437,561 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,165 research outputs from this source. They receive a mean Attention Score of 3.5. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 251,810 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 26 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.