Peer 1
Fig. 1a contains several graphs with different conditions.I separated these graphs using Adobe Illustrator.http://i.imgur.com/umh75EY...
Fig. 1a contains several graphs with different conditions.I separated these graphs using Adobe Illustrator.http://i.imgur.com/umh75EY...
A correction of the data aboveThe height of the center of the ellipse is not −5.46 mm but −5.666 mm, vertically relative to bregma...
In this article we report the simulated placement of a probe.The probe was inserted with a guide cannula into the dorsal raphe nucleus (DRN; A = −8...
I can understand why do not authors reply to Peer1~3.All comments of Peer1~3 are made by their incorrect knowledge and malicious.I agree with many peers comments to Peer1~3...
>Unregistered Submission:( May 30th, 2015 9:46am UTC )“I haven't ever heard such a strong statistical analysis for making a significant difference...
I haven't ever heard such a strong statistical analysis for making a significant difference.Could you show us how to conduct ANOVA or MANOVA in deta, e...
>Peer 2: ( December 30th, 2014 9:54am UTC )"The value of blue arrow and red one are almost equal.The error bar of blue arrow is smaller than red one...
Although I can agree with Peer1’on December 30th, 2014 when using ANOVA, the results were analysed by MANOVA.Conclusion of Peer1 are rejected by statistics
>Peer 3: ( December 30th, 2014 11:28pm UTC )>Peer 1: ( January 4th, 2015 11:41am UTC )>Peer 3: ( January 4th, 2015 6:17pm UTC )>Peer 1: ( January 4th, 2015 11:08pm UTC )All microdialysis researchers…
All microdialysis researchers must not agree with the statistical analysis comments of Peer1 and Peer3. Peer 3: ( December 30th, 2014 11:28pm UTC )Peer 1: ( January 4th, 2015 11:41am UTC )Peer 3: …
>Unregistered Submission: ( May 25th, 2015 6:50am UTC )"Many peers think it's impossible to avoid the cerebral aqueduct with their method...
Reports of Peer1 are elegant, but does not compose of scientific or professional comments.
Whether or not the error bars for each group overlap tells us nothing about the P value of a paired t test or repeated ANOVA.This rule works for both paired and unpaired t tests...
I have already commented on the point in this thread at 8:12am UTC on December 30th, 2014 https://pubpeer.com/publications/6ECDA476D996AB53B46775B083EE83#fb19753
> UnregThe same issue with the same comments is discussed in other their paper.https://pubpeer.com/publications/2C78A52434048FBB59E4CB7342F743#fb30623Many peers think it's impossible to avoid the…
The probe position (Peer1: December 26th, 2014) is obviously wrong and different position from original position (A=−8.2 mm, L=0.2 mm, V=−6...
In the web page indicated by Peer2, I can find out the important comments.Whether or not the error bars for each group overlap tells you nothing about the P value of a paired t test...
This paper has the same problem in the statistics.https://pubpeer.com/publications/478C71F68A43CC1E6BBDD9415D5D05
It's more general than "MANOVA + Tukey's". The problem arises as soon as the ANOVA family of tests is used, as they assume "homogeneity of variance", in other words that the variance of each sample…
>Peer 3,I understand. Thank you for taking the time for me. I appreciate your continued support.
Thank you so much for your advice.I have already noticed these problems to the editor-in-chief. He promised me to make an investigation in Mie University to which the authors belong...
>Peer 3Is it inappropriate to use MANOVA with Tukey's multiple comparison in the case that variances in each group are not equal like those figueres in this paper?
So, how to get the ball rolling? First, contact ALL editors of Psychopharmacology, not just the EIC.http://www.springer.com/biomed/neuroscience/journal/213 http://www...
The methods have this to say about the statistical analysis."Data were expressed as mean [plus or minus] SEM. The dose-dependent effects of systemically administered CBZ and LTG on extracellular…
Dr. Tanahashi or unreg,In fact, I'm not a specialist of statics, and am afraid of misunderstanding of this issue.To make a proof of your work (if you are one of the authors), how about showing us…
>Regarding Peer2’s allegation of statistical analysis.I'll show you other figures in the different article of the authors' group (Yamamura et al...
>Regarding Peer1' s allegation of probe position and its angle.The center of the tip of the probe is (A = - 8.2 mm, L = 0.2 mm, V = - 6...
@ unreg, are you Dr. Tanahashi?Thank you very much for your reply and lecture about your statistic analysis.I'm so impressed.In spite of your correct understanding for MANOVA, I have some questions…
Regarding Peer1’s allegation of probe position and its angle.Peer1 described that “The position of the probe according to the article is illustrated as agreen ellipse in the images...
Are there also unnatural graph, like other their work?https://pubpeer.com/publications/F1063251242525B9DCF8F624B2F61Ehttps://pubpeer...
These error bars are SEM!? And with significance < 0.05? How many animals (n) did they use for this graph?
They state "Data are mean ± SEM (n=6) of extracellular serotonin level (nM). The abscissas represent time after administration (min). The dose-dependent effects of LTG and CBZ were compared using…
Fig. 2bThe differences between the post-treatment and pre-treatment in the closed circles are relatively small and the SEM values are relatively large; however, the authors state that the differences…
The angle used in the method in this article is too small to avoid the cerebral aqueduct although the authors state "Specifically,the DRN probe was implanted at an angle of 10° from the vertical to…
You mean the method the authors used is theoroticaly impossible in all of their papers?
Yes, I think that we cannot detect serotonin using their method.