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Selective inhibition of 12-lipoxygenase protects islets and beta cells from inflammatory cytokine-mediated beta cell dysfunction

Overview of attention for article published in Diabetologia, November 2014
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  • Average Attention Score compared to outputs of the same age and source

Mentioned by

twitter
4 tweeters

Citations

dimensions_citation
17 Dimensions

Readers on

mendeley
21 Mendeley
Title
Selective inhibition of 12-lipoxygenase protects islets and beta cells from inflammatory cytokine-mediated beta cell dysfunction
Published in
Diabetologia, November 2014
DOI 10.1007/s00125-014-3452-0
Pubmed ID
Authors

David A. Taylor-Fishwick, Jessica Weaver, Lindsey Glenn, Norine Kuhn, Ganesha Rai, Ajit Jadhav, Anton Simeonov, Angela Dudda, Dieter Schmoll, Theodore R. Holman, David J. Maloney, Jerry L. Nadler

Abstract

Islet inflammation leads to loss of functional pancreatic beta cell mass. Increasing evidence suggests that activation of 12-lipoxygenase leads to inflammatory beta cell loss. This study evaluates new specific small-molecule inhibitors of 12-lipoxygenase for protecting rodent and human beta cells from inflammatory damage.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Other 7 33%
Researcher 6 29%
Professor 4 19%
Student > Master 2 10%
Student > Ph. D. Student 1 5%
Other 1 5%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 7 33%
Medicine and Dentistry 7 33%
Agricultural and Biological Sciences 3 14%
Chemistry 2 10%
Immunology and Microbiology 2 10%
Other 0 0%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 February 2015.
All research outputs
#7,339,428
of 12,225,951 outputs
Outputs from Diabetologia
#2,955
of 3,621 outputs
Outputs of similar age
#127,589
of 271,321 outputs
Outputs of similar age from Diabetologia
#49
of 79 outputs
Altmetric has tracked 12,225,951 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,621 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.1. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 271,321 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 79 others from the same source and published within six weeks on either side of this one. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.