Reviewing Approaches to Improving Aged Stem Cell Function
Fight Aging!,
A variety of approaches show some promise in improving the function of stem cells in aged tissues. Stem cell populations…
A variety of approaches show some promise in improving the function of stem cells in aged tissues. Stem cell populations…
Researchers here report on work that identifies SOX17 inhibition as a potential way to attack colon cancer in its early stages.
Dysregulation of nutrient sensing is one of the hallmarks of aging, and the work here illustrates that this dysregulation has…
The intestinal barrier becomes leaky with age, allowing microbes and unwanted metabolites in the gut access to the body, where…
The lifespan of flies is especially sensitive to intestinal function, making them perhaps an interesting model in which to…
Senescent cells are constantly created and destroyed in all tissues of the body throughout life, but the number present at any…
The inhibition of CDC42 is starting to look like a most interesting intervention, based on the animal data produced over the…
The practice of calorie restriction improves many measures of health, and extends life meaningfully in short lived species such…
The practice of calorie restriction, eating up to 40% fewer calories while still maintaining an optimal intake of micronutrients…
Researchers here investigate the relationship between the protein complex mTORC1 and the aging of intestinal stem cells…
In aging flies, we can consider degeneration of intestinal tissue and function as the primary cause of mortality, in much the…
Efficient DNA repair is necessary to prevent cells from becoming dysfunctional or senescent in response to stochastic nuclear…
Nicotinamide riboside supplementation is one of the ways to increase levels of NAD+ in mitochondria, thus improving…
Today I'll point out a demonstration of one of the many ways in which calorie restriction and fasting improve matters in our…
Researchers here find that inhibition of Wnt signaling can improve the state of cartilage and joint function in a mouse model…