Title |
Low-FODMAP Diet for Irritable Bowel Syndrome: Is It Ready for Prime Time?
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Published in |
Digestive Diseases and Sciences, November 2014
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DOI | 10.1007/s10620-014-3436-4 |
Pubmed ID | |
Authors |
Muhammad Ali Khan, Salman Nusrat, Muhammad Imran Khan, Ali Nawras, Klaus Bielefeldt |
Abstract |
Irritable bowel syndrome (IBS) is a chronic gastrointestinal disease, which adversely affects the quality of life. Its prevalence has been reported to be around 10-15 % in North America and constitutes the most common cause for gastroenterology referral. Unfortunately, the pathophysiology of IBS is not completely understood. Not surprisingly, the management strategies can leave the patients with inadequate symptom control, making IBS a debilitating gastrointestinal syndrome. Dietary interventions as a treatment strategy for IBS have been recently evaluated. One such intervention includes dietary restriction of fermentable oligo-, di-, and monosaccharides and polyols (FODMAPs). FODMAPs define a group of short-chain carbohydrates that are incompletely absorbed in small intestine and later fermented in the colon. Evidence in the form of randomized controlled trials and observational studies have evaluated the mechanism of action and efficacy of low-FODMAP diet. This dietary intervention has showed promising results in symptom reduction in IBS patients. However, latest trials have also shown that the low-FODMAP diet is associated with marked changes in gut microbiota specifically reduction in microbiota with prebiotic properties. Implications of such changes on gastrointestinal health need to be further evaluated in future trials. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 8 | 25% |
United States | 5 | 16% |
Spain | 2 | 6% |
Ireland | 2 | 6% |
Australia | 1 | 3% |
India | 1 | 3% |
Belgium | 1 | 3% |
Japan | 1 | 3% |
Venezuela, Bolivarian Republic of | 1 | 3% |
Other | 0 | 0% |
Unknown | 10 | 31% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 18 | 56% |
Practitioners (doctors, other healthcare professionals) | 13 | 41% |
Scientists | 1 | 3% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 2 | 1% |
Chile | 1 | <1% |
Unknown | 169 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 44 | 26% |
Student > Master | 26 | 15% |
Researcher | 17 | 10% |
Student > Ph. D. Student | 14 | 8% |
Other | 13 | 8% |
Other | 24 | 14% |
Unknown | 34 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 57 | 33% |
Agricultural and Biological Sciences | 27 | 16% |
Nursing and Health Professions | 26 | 15% |
Biochemistry, Genetics and Molecular Biology | 9 | 5% |
Social Sciences | 4 | 2% |
Other | 12 | 7% |
Unknown | 37 | 22% |