Title |
Molecular Characterization of Toxigenic Clostridium difficile in a Northern Italian Hospital
|
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Published in |
Current Microbiology, September 2014
|
DOI | 10.1007/s00284-014-0690-9 |
Pubmed ID | |
Authors |
Francesco G. De Rosa, Paolo Cavallerio, Silvia Corcione, Caterina Parlato, Lucina Fossati, Roberto Serra, Giovanni Di Perri, Rossana Cavallo |
Abstract |
Clostridium difficile is responsible for more than 90 % of cases of antibiotic-associated diarrhea and pseudomembranous colitis. The most important virulence factors are two toxins called enterotoxin A and cytotoxin B; some C. difficile strains contain the C. difficile binary toxin (CDT). The aim of our study was to prospectively analyze C. difficile clinical isolates in a single center to determine the molecular features of collected strains. Among the 252 isolates, 217 were A + B + (86.1 %), 33 were A + B + cdt + (13.1 %) and 2 were A - B + (0.8 %). There were 15 different ribotypes with a predominance of 018. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 14 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 2 | 14% |
Professor > Associate Professor | 2 | 14% |
Student > Ph. D. Student | 2 | 14% |
Student > Doctoral Student | 1 | 7% |
Student > Bachelor | 1 | 7% |
Other | 3 | 21% |
Unknown | 3 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 4 | 29% |
Agricultural and Biological Sciences | 2 | 14% |
Immunology and Microbiology | 2 | 14% |
Physics and Astronomy | 1 | 7% |
Biochemistry, Genetics and Molecular Biology | 1 | 7% |
Other | 0 | 0% |
Unknown | 4 | 29% |