Title |
Far from the Eyes, Close to the Heart: Dysbiosis of Gut Microbiota and Cardiovascular Consequences
|
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Published in |
Current Cardiology Reports, October 2014
|
DOI | 10.1007/s11886-014-0540-1 |
Pubmed ID | |
Authors |
Matteo Serino, Vincent Blasco-Baque, Simon Nicolas, Remy Burcelin |
Abstract |
These days, the gut microbiota is universally recognized as an active organ that can modulate the overall host metabolism by promoting multiple functions, from digestion to the systemic maintenance of overall host physiology. Dysbiosis, the alteration of the complex ecologic system of gut microbes, is associated with and causally responsible for multiple types of pathologies. Among the latters, metabolic diseases such as type 2 diabetes and obesity are each distinguishable by a unique gut microbiota profile. Interestingly, the specific microbiota typically found in the blood of diabetic patients also has been observed at the level of atherosclerotic plaque. Here, we report evidence from the literature, as well as a few controversial reports, regarding the putative role of gut microbiota dysbiosis-induced cardiovascular diseases, such as atherosclerosis, which are common comorbidities of metabolic dysfunction. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 4 | 50% |
Unknown | 4 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 7 | 88% |
Practitioners (doctors, other healthcare professionals) | 1 | 13% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | <1% |
India | 1 | <1% |
Portugal | 1 | <1% |
Unknown | 219 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 46 | 21% |
Student > Master | 29 | 13% |
Student > Ph. D. Student | 28 | 13% |
Student > Bachelor | 28 | 13% |
Other | 14 | 6% |
Other | 34 | 15% |
Unknown | 43 | 19% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 53 | 24% |
Agricultural and Biological Sciences | 29 | 13% |
Biochemistry, Genetics and Molecular Biology | 25 | 11% |
Immunology and Microbiology | 14 | 6% |
Nursing and Health Professions | 13 | 6% |
Other | 31 | 14% |
Unknown | 57 | 26% |