Title |
Icosapent Ethyl, a Pure Ethyl Ester of Eicosapentaenoic Acid: Effects on Circulating Markers of Inflammation from the MARINE and ANCHOR Studies
|
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Published in |
American Journal of Cardiovascular Drugs, January 2013
|
DOI | 10.1007/s40256-012-0002-3 |
Pubmed ID | |
Authors |
Harold E. Bays, Christie M. Ballantyne, Rene A. Braeckman, William G. Stirtan, Paresh N. Soni |
Abstract |
Icosapent ethyl (IPE) is a high-purity prescription form of eicosapentaenoic acid ethyl ester approved by the US Food and Drug Administration as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe (≥500 mg/dL) hypertriglyceridemia. In addition to TG-lowering effects, IPE also reduces non-high-density lipoprotein cholesterol and apolipoprotein B levels without significantly increasing low-density lipoprotein cholesterol (LDL-C) in patients with very high TG levels ≥500 mg/dL (MARINE study) and in patients with well-controlled LDL-C and residually high TG levels 200-500 mg/dL (ANCHOR study). This analysis examined the effect of IPE on inflammatory markers in patients from MARINE and ANCHOR. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 1% |
Singapore | 1 | 1% |
Romania | 1 | 1% |
Unknown | 94 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 16 | 16% |
Other | 11 | 11% |
Student > Bachelor | 11 | 11% |
Student > Ph. D. Student | 10 | 10% |
Student > Doctoral Student | 7 | 7% |
Other | 15 | 15% |
Unknown | 27 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 35 | 36% |
Biochemistry, Genetics and Molecular Biology | 8 | 8% |
Agricultural and Biological Sciences | 5 | 5% |
Immunology and Microbiology | 4 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 4% |
Other | 12 | 12% |
Unknown | 29 | 30% |