Title |
Siltuximab: First Global Approval
|
---|---|
Published in |
Drugs, June 2014
|
DOI | 10.1007/s40265-014-0249-x |
Pubmed ID | |
Authors |
Anthony Markham, Trina Patel |
Abstract |
The anti-interleukin-6 (IL-6) chimeric monoclonal antibody siltuximab is the first drug to be approved for the treatment of multicentric Castleman's disease (MCD) in the US and European union (EU), having gained approval under the FDA priority review program in the US and from an accelerated assessment and recommendation by the Committee for Medicinal Products for Human Use (CHMP) in the EU. Development of the drug is continuing in smoldering multiple myeloma. This article summarizes the milestones in the development of siltuximab leading to this first approval for MCD. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 24 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 4 | 17% |
Researcher | 3 | 13% |
Lecturer | 2 | 8% |
Student > Postgraduate | 2 | 8% |
Student > Ph. D. Student | 2 | 8% |
Other | 3 | 13% |
Unknown | 8 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 9 | 38% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 8% |
Biochemistry, Genetics and Molecular Biology | 2 | 8% |
Chemical Engineering | 1 | 4% |
Neuroscience | 1 | 4% |
Other | 0 | 0% |
Unknown | 9 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 June 2023.
All research outputs
#6,467,510
of 22,953,506 outputs
Outputs from Drugs
#1,114
of 3,283 outputs
Outputs of similar age
#61,565
of 228,664 outputs
Outputs of similar age from Drugs
#18
of 44 outputs
Altmetric has tracked 22,953,506 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 3,283 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,664 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.