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Autologous and micro‐fragmented adipose tissue for the treatment of diffuse degenerative knee osteoarthritis

Overview of attention for article published in Journal of Experimental Orthopaedics, October 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#44 of 333)
  • Good Attention Score compared to outputs of the same age (74th percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

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Citations

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104 Mendeley
Title
Autologous and micro‐fragmented adipose tissue for the treatment of diffuse degenerative knee osteoarthritis
Published in
Journal of Experimental Orthopaedics, October 2017
DOI 10.1186/s40634-017-0108-2
Pubmed ID
Authors

A. Russo, V. Condello, V. Madonna, M. Guerriero, C. Zorzi

Abstract

Chondral lesions of the knee represent a challenge for the orthopaedic surgeon. Several treatments have been proposed with variable success rate. Recently, new therapeutic approaches, such as the use of mesenchymal stem cells, have shown promising results. The adipose tissue is a good source of these naturally occurring regenerative cells, due to its abundance and easy access. In addition, it can be used to provide cushioning and filling of structural defects. The 1-year safety and outcome of a single intra-articular injection of autologous and micro-fragmented adipose tissue in 30 patients affected by diffuse degenerative chondral lesions was evaluated. Micro-fragmented adipose tissue was obtained using a minimal manipulation technique in a closed system. The safety of the procedure was evaluated by recording type and incidence of any adverse event. The clinical outcomes were determined using the KOOS, IKDC-subjective, Tegner Lysholm Knee, and VAS pain scales taken pre-operatively and at 12 months follow-up. A level of at least 10 points of improvement in the scores has been selected as cut-off representing a clinically significant difference. No relevant complications nor clinical worsening were recorded. A total median improvement of 20 points has been observed in IKDC-subjective and total KOOS, and a higher percentage of success was found in VAS pain and Tegner Lysholm Knee, where the total median improvement was 24 and 31 points, respectively. The results of this study show the safety and feasibility of using autologous and micro-fragmented adipose tissue in patients affected by diffuse degenerative chondral lesions. The technique is safe, minimally invasive, simple, one-step, with low percentage of complications, and compliant with the regulatory panorama.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 104 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 104 100%

Demographic breakdown

Readers by professional status Count As %
Other 15 14%
Researcher 15 14%
Student > Bachelor 13 13%
Student > Master 7 7%
Student > Doctoral Student 6 6%
Other 13 13%
Unknown 35 34%
Readers by discipline Count As %
Medicine and Dentistry 38 37%
Biochemistry, Genetics and Molecular Biology 7 7%
Nursing and Health Professions 5 5%
Agricultural and Biological Sciences 4 4%
Veterinary Science and Veterinary Medicine 2 2%
Other 10 10%
Unknown 38 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 December 2017.
All research outputs
#4,644,865
of 23,005,189 outputs
Outputs from Journal of Experimental Orthopaedics
#44
of 333 outputs
Outputs of similar age
#82,750
of 323,064 outputs
Outputs of similar age from Journal of Experimental Orthopaedics
#1
of 6 outputs
Altmetric has tracked 23,005,189 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 333 research outputs from this source. They receive a mean Attention Score of 4.2. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 323,064 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them