| Title |
Assessing the Transfer of Genetically Modified DNA from Feed to Animal Tissues
|
|---|---|
| Published in |
Transgenic Research, October 2005
|
| DOI | 10.1007/s11248-005-0009-5 |
| Pubmed ID | |
| Authors |
Raffaele Mazza, Mirko Soave, Mauro Morlacchini, Gianfranco Piva, Adriano Marocco |
| Abstract |
In Europe, public and scientific concerns about the environmental and food safety of GM (Genetically Modified) crops overshadow the potential benefits offered by crop biotechnology to improve food quality. One of the concerns regarding the use of GM food in human and animal nutrition is the effect that newly introduced sequences may have on the organism. In this paper, we assess the potential transfer of diet-derived DNA to animal tissues after consumption of GM plants. Blood, spleen, liver, kidney and muscle tissues from piglets fed for 35 days with diets containing either GM (MON810) or a conventional maize were investigated for the presence of plant DNA. Only fragments of specific maize genes (Zein, Sh-2) could be detected with different frequencies in all the examined tissues except muscle. A small fragment of the Cry1A(b) transgene was detected in blood, liver, spleen and kidney of the animals raised with the transgenic feed. The intact Cry1A(b) gene or its minimal functional unit were never detected. Statistical analysis of the results showed no difference in recovery of positives for the presence of plant DNA between animals raised with the transgenic feed and animals raised with the conventional feed, indicating that DNA transfer may occur independently from the source and the type of the gene. From the data obtained, we consider it unlikely that the occurrence of genetic transfer associated with GM plants is higher than that from conventional plants. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 6 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 83% |
| Science communicators (journalists, bloggers, editors) | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 3 | 4% |
| France | 1 | 1% |
| South Africa | 1 | 1% |
| Italy | 1 | 1% |
| Iceland | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 73 | 90% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 20 | 25% |
| Student > Bachelor | 17 | 21% |
| Student > Ph. D. Student | 10 | 12% |
| Student > Master | 8 | 10% |
| Professor | 6 | 7% |
| Other | 11 | 14% |
| Unknown | 9 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 42 | 52% |
| Biochemistry, Genetics and Molecular Biology | 10 | 12% |
| Chemistry | 3 | 4% |
| Environmental Science | 3 | 4% |
| Earth and Planetary Sciences | 3 | 4% |
| Other | 7 | 9% |
| Unknown | 13 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 October 2021.
All research outputs
#2,044,119
of 24,712,008 outputs
Outputs from Transgenic Research
#53
of 940 outputs
Outputs of similar age
#3,176
of 64,040 outputs
Outputs of similar age from Transgenic Research
#3
of 12 outputs
Altmetric has tracked 24,712,008 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 940 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 64,040 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.