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Epidemiology and Clinical Aspects of HPV in Head and Neck Cancers

Overview of attention for article published in Head and Neck Pathology, July 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#2 of 140)
  • Good Attention Score compared to outputs of the same age (79th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

blogs
1 blog

Citations

dimensions_citation
140 Dimensions

Readers on

mendeley
136 Mendeley
Title
Epidemiology and Clinical Aspects of HPV in Head and Neck Cancers
Published in
Head and Neck Pathology, July 2012
DOI 10.1007/s12105-012-0377-0
Pubmed ID
Authors

Anil K. Chaturvedi

Abstract

Human papillomavirus (HPV) infection is now established as a major etiologic factor for oropharyngeal cancers. Case-control studies conducted around the world show strong and consistent associations of markers of HPV exposure with risk of oropharyngeal cancers (range of odds ratios [OR] for oral oncogenic HPV infections = 3.6-230.0, ORs for HPV16 L1 antibodies = 2.3-182.0, and ORs for HPV16 E6/E7 antibodies = 9.2-231.0. HPV-positive oropharyngeal cancers are epidemiologically distinct from HPV-negative ones, and are characterized by younger age at onset, male predominance, and strong association with sexual behaviors. Importantly, HPV-positive oropharyngeal cancer patients have substantially improved outcomes (28-80 % reductions in the risk of death) than HPV-negative patients. Given the superior survival, younger age, and good performance status of HPV-positive oropharyngeal cancer patients, de-intensified therapies are currently being considered for this group of patients. Recent analyses of cancer registry data show dramatic increases in incidence of oropharyngeal cancers during the past 15-20 years in several parts of the world, highlighting the need for prevention strategies. If proven efficacious, currently available prophylactic HPV vaccines hold great promise for primary prevention of HPV-associated oropharyngeal cancers.

Mendeley readers

The data shown below were compiled from readership statistics for 136 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 1%
United Kingdom 2 1%
Tanzania, United Republic of 1 <1%
Philippines 1 <1%
Spain 1 <1%
Unknown 129 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 24 18%
Student > Master 24 18%
Researcher 19 14%
Student > Doctoral Student 14 10%
Unspecified 12 9%
Other 43 32%
Readers by discipline Count As %
Medicine and Dentistry 81 60%
Unspecified 21 15%
Agricultural and Biological Sciences 15 11%
Biochemistry, Genetics and Molecular Biology 8 6%
Engineering 3 2%
Other 8 6%

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 July 2014.
All research outputs
#687,043
of 4,057,236 outputs
Outputs from Head and Neck Pathology
#2
of 140 outputs
Outputs of similar age
#19,940
of 101,216 outputs
Outputs of similar age from Head and Neck Pathology
#1
of 14 outputs
Altmetric has tracked 4,057,236 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 140 research outputs from this source. They receive a mean Attention Score of 0.9. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 101,216 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.