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Autophagy and inflammation

Overview of attention for article published in Clinical and Translational Medicine, July 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#21 of 170)
  • High Attention Score compared to outputs of the same age (84th percentile)

Mentioned by

news
1 news outlet
twitter
6 tweeters
facebook
1 Facebook page

Citations

dimensions_citation
47 Dimensions

Readers on

mendeley
142 Mendeley
Title
Autophagy and inflammation
Published in
Clinical and Translational Medicine, July 2017
DOI 10.1186/s40169-017-0154-5
Pubmed ID
Authors

Mengjia Qian, Xiaocong Fang, Xiangdong Wang

Abstract

Autophagy is a homeostatic mechanism involved in the disposal of damaged organelles, denatured proteins as well as invaded pathogens through a lysosomal degradation pathway. Recently, increasing evidences have demonstrated its role in both innate and adaptive immunity, and thereby influence the pathogenesis of inflammatory diseases. The detection of autophagy machinery facilitated the measurement of autophagy during physiological and pathophysiological processes. Autophagy plays critical roles in inflammation through influencing the development, homeostasis and survival of inflammatory cells, including macrophages, neutrophils and lymphocytes; effecting the transcription, processing and secretion of a number of cytokines, as well as being regulated by cytokines. Recently, autophagy-dependent mechanisms have been studied in the pathogenesis of several inflammatory diseases, including infectious diseases, Crohn's disease, cystic fibrosis, pulmonary hypertension, chronic obstructive pulmonary diseases and so on. These studies suggested that modulation of autophagy might lead to therapeutic interventions for diseases associated with inflammation. Here we highlight recent advances in investigating the roles of autophagy in inflammation as well as inflammatory diseases.

Twitter Demographics

The data shown below were collected from the profiles of 6 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 142 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 142 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 30 21%
Researcher 23 16%
Unspecified 23 16%
Student > Master 18 13%
Student > Bachelor 17 12%
Other 31 22%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 32 23%
Unspecified 24 17%
Agricultural and Biological Sciences 23 16%
Medicine and Dentistry 20 14%
Immunology and Microbiology 20 14%
Other 23 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 February 2019.
All research outputs
#1,168,429
of 12,942,974 outputs
Outputs from Clinical and Translational Medicine
#21
of 170 outputs
Outputs of similar age
#39,539
of 264,212 outputs
Outputs of similar age from Clinical and Translational Medicine
#1
of 1 outputs
Altmetric has tracked 12,942,974 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 170 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.9. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,212 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them