↓ Skip to main content

Hepatitis B reactivation after chemotherapy: two decades of clinical research

Overview of attention for article published in Hepatology International, March 2008
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#13 of 230)
  • High Attention Score compared to outputs of the same age (83rd percentile)

Mentioned by

policy
1 policy source
twitter
2 tweeters
patent
2 patents

Citations

dimensions_citation
72 Dimensions

Readers on

mendeley
19 Mendeley
Title
Hepatitis B reactivation after chemotherapy: two decades of clinical research
Published in
Hepatology International, March 2008
DOI 10.1007/s12072-008-9056-3
Pubmed ID
Authors

George K. K. Lau

Abstract

Hepatitis due to hepatitis B virus reactivation after cytotoxic or immunosuppressive therapy is a serious cause of liver-related morbidity and mortality. With the characterization of the underlying pathogenesis, much progress in the management of this important clinical problem has been made in the past 2 decades. By year 2008, it is mandatory to screen for hepatitis B surface antigen status before initiating intensive chemotherapy or immunosuppressive therapy. All those who are hepatitis B surface antigen positive should be started on preemptive nucleos(t)ide analogues. However, there remains important issues, such as the type and duration of nucleos(t)ide analogue therapy, which need to be understood. As not all hepatitis B surface antigen-positive patients will suffer from HBV reactivation, it is therefore useful to identify risk factors related to HBV reactivation so that patients will not be treated unnecessarily with nucleos(t)ide analogues. To date, a high baseline level of viral replication, as reflected by high serum HBV DNA level, positive serum hepatitis B e antigen, and a high intrahepatic covalently closed circular DNA level, is the most important predictor for HBV reactivation. Recently, there has been an increased awareness of reactivation of occult hepatitis B virus, especially in hepatitis B virus endemic area, such as the Asia-Pacific region. Careful epidemiological study will be needed to clarify the impact of occult hepatitis B infection in patients treated with cytotoxic or immunosuppressive therapy.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 5%
Unknown 18 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 32%
Other 3 16%
Student > Master 3 16%
Student > Bachelor 2 11%
Student > Ph. D. Student 2 11%
Other 3 16%
Readers by discipline Count As %
Medicine and Dentistry 12 63%
Agricultural and Biological Sciences 3 16%
Nursing and Health Professions 1 5%
Biochemistry, Genetics and Molecular Biology 1 5%
Social Sciences 1 5%
Other 1 5%

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2019.
All research outputs
#2,111,458
of 13,511,623 outputs
Outputs from Hepatology International
#13
of 230 outputs
Outputs of similar age
#31,479
of 190,517 outputs
Outputs of similar age from Hepatology International
#1
of 3 outputs
Altmetric has tracked 13,511,623 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 230 research outputs from this source. They receive a mean Attention Score of 2.5. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 190,517 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them