Title |
Biological activity of lipopeptides from Bacillus
|
---|---|
Published in |
Applied Microbiology and Biotechnology, July 2017
|
DOI | 10.1007/s00253-017-8396-0 |
Pubmed ID | |
Authors |
Haobin Zhao, Dongyan Shao, Chunmei Jiang, Junling Shi, Qi Li, Qingsheng Huang, Muhammad Shahid Riaz Rajoka, Hui Yang, Mingliang Jin |
Abstract |
The lipopeptides of Bacillus are small metabolites that contain a cyclic structure formed by 7-10 amino acids (including 2-4 D-amino acids) and a beta-hydroxy fatty acid with 13-19 C atoms. These lipopeptides exhibit a variety of biological activities, including interactions with biofilms, and anti-fungal, anti-inflammatory, anti-tumor, anti-virus, and anti-platelet properties. The multiple activities of lipopeptides have stimulated significant interest in the exploitation of these lipopeptides for use as antibiotics, feed additives, anti-tumor agents, urgent thrombolytic therapeutic agents, and drug delivery systems. Understanding the natural function of these structurally diverse lipopeptides in Bacillus provides insight into microbial regulatory programs and is required for efficient development of more effective products. Currently, there is still insufficient knowledge of the direct target of these lipopeptides, and continued efforts are needed to enhance their biosynthesis efficiency for industrial applications. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 33% |
Mexico | 1 | 33% |
Netherlands | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Scientists | 2 | 67% |
Members of the public | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 335 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 49 | 15% |
Student > Ph. D. Student | 46 | 14% |
Student > Doctoral Student | 28 | 8% |
Researcher | 27 | 8% |
Student > Bachelor | 20 | 6% |
Other | 59 | 18% |
Unknown | 106 | 32% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 80 | 24% |
Biochemistry, Genetics and Molecular Biology | 65 | 19% |
Immunology and Microbiology | 11 | 3% |
Chemistry | 9 | 3% |
Engineering | 8 | 2% |
Other | 42 | 13% |
Unknown | 120 | 36% |