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Corin in Natriuretic Peptide Processing and Hypertension

Overview of attention for article published in Current Hypertension Reports, January 2014
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age and source (55th percentile)

Mentioned by

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1 tweeter

Citations

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30 Dimensions

Readers on

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3 Mendeley
Title
Corin in Natriuretic Peptide Processing and Hypertension
Published in
Current Hypertension Reports, January 2014
DOI 10.1007/s11906-013-0415-7
Pubmed ID
Authors

Yiqing Zhou, Qingyu Wu

Abstract

Corin is a serine protease originally isolated from the heart. Functional studies show that corin is the long-sought enzyme responsible for activating cardiac natriuretic peptides. In mice, lack of corin prevents natriuretic peptide processing, causing salt-sensitive hypertension. In humans, corin variants and mutations that reduce corin activity have been identified in patients with hypertension and heart failure. Decreased plasma levels of corin antigen and activity have been reported in patients with heart failure and coronary artery disease. Low levels of urinary corin also have been found in patients with chronic kidney disease. Most recent studies show that corin also acts in the uterus to promote spiral artery remodeling and prevent pregnancy-induced hypertension. Here, we review the role of corin in natriuretic peptide processing and cardiovascular diseases such as hypertension, heart disease, pre-eclampsia, and chronic kidney disease.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 3 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 3 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 1 33%
Student > Ph. D. Student 1 33%
Unspecified 1 33%
Readers by discipline Count As %
Medicine and Dentistry 2 67%
Immunology and Microbiology 1 33%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 March 2014.
All research outputs
#9,995,247
of 12,488,170 outputs
Outputs from Current Hypertension Reports
#316
of 466 outputs
Outputs of similar age
#127,578
of 188,277 outputs
Outputs of similar age from Current Hypertension Reports
#3
of 9 outputs
Altmetric has tracked 12,488,170 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 466 research outputs from this source. They receive a mean Attention Score of 3.8. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 188,277 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.