Observation of “Seesaw Effect” with Vancomycin, Teicoplanin, Daptomycin and Ceftaroline in 150 Unique MRSA Strains

RT @MWaqarSharifMD: Today I learnt seesaw effect. Proposed mechanisms underpinning Vanc/Daptomycin + β-lactam therapy invoke synergy and th…

Today I learnt seesaw effect. Proposed mechanisms underpinning Vanc/Daptomycin + β-lactam therapy invoke synergy and the so-called “seesaw effect” generally observed in MRSA infections. ID is not that boring. More Read on https://t.co/CbErbJYCc9 #Medtwitte

One of my fave concepts #IDtwitter #TwitteRx

Heard of the “seesaw effect”?⚖️ In S. aureus bacteremia, simultaneous exposure to glyco- or lipopeptides and antistaph B-lactams leads to an inverse relationship between the MICs (⬆️ susceptibility to BL, ⬇️ susceptibility to LP/GP) @MK_IDpharm #TwitteRx

#OTILT Ceftaroline used in combination with Vancomycin, Daptomycin, or Teicoplanin has demonstrated a "Seesaw Effect", where Ceftaroline susceptibility increased as MICs for the other drugs increased against MRSA in vitro. https://t.co/L4dHe5Bvhc @BWDionne

Observation of “Seesaw Effect” with Vancomycin, Teicoplanin, Daptomycin and Ceftaroline in 150 Unique MRSA... http://t.co/S2B6pyGDfu #mrsa