Title |
Expanding the range of polyhydroxyalkanoates synthesized by methanotrophic bacteria through the utilization of omega-hydroxyalkanoate co-substrates
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Published in |
AMB Express, June 2017
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DOI | 10.1186/s13568-017-0417-y |
Pubmed ID | |
Authors |
Jaewook Myung, James C. A. Flanagan, Robert M. Waymouth, Craig S. Criddle |
Abstract |
The first methanotrophic syntheses of polyhydroxyalkanoates (PHAs) that contain repeating units beyond 3-hydroxybutyrate and 3-hydroxyvalerate are reported. New PHAs synthesized by methanotrophs include poly(3-hydroxybutyrate-co-4-hydroxybutyrate) (P(3HB-co-4HB)), poly(3-hydroxybutyrate-co-5-hydroxyvalerate-co-3-hydroxyvalerate) (P(3HB-co-5HV-co-3HV)), and poly(3-hydroxybutyrate-co-6-hydroxyhexanoate-co-4-hydroxybutyrate) (P(3HB-co-6HHx-co-4HB)). This was achieved from a pure culture of Methylocystis parvus OBBP where the primary substrate is methane and the corresponding ω-hydroxyalkanoate monomers are added as a co-substrate after the cells are subjected to nitrogen-limited conditions. |
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Unknown | 1 | 100% |
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Members of the public | 1 | 100% |
Mendeley readers
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Unknown | 79 | 100% |
Demographic breakdown
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Student > Ph. D. Student | 21 | 27% |
Student > Master | 11 | 14% |
Researcher | 10 | 13% |
Student > Bachelor | 5 | 6% |
Professor | 4 | 5% |
Other | 6 | 8% |
Unknown | 22 | 28% |
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Engineering | 11 | 14% |
Agricultural and Biological Sciences | 9 | 11% |
Environmental Science | 8 | 10% |
Biochemistry, Genetics and Molecular Biology | 7 | 9% |
Chemistry | 5 | 6% |
Other | 12 | 15% |
Unknown | 27 | 34% |