↓ Skip to main content

New fronts emerge in the influenza cytokine storm

Overview of attention for article published in Seminars in Immunopathology, May 2017
Altmetric Badge

About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (61st percentile)
  • Good Attention Score compared to outputs of the same age and source (73rd percentile)

Mentioned by

twitter
5 tweeters

Citations

dimensions_citation
24 Dimensions

Readers on

mendeley
48 Mendeley
Title
New fronts emerge in the influenza cytokine storm
Published in
Seminars in Immunopathology, May 2017
DOI 10.1007/s00281-017-0636-y
Pubmed ID
Authors

Xi-zhi J. Guo, Paul G. Thomas

Abstract

Influenza virus is a significant pathogen in humans and animals with the ability to cause extensive morbidity and mortality. Exuberant immune responses induced following infection have been described as a "cytokine storm," associated with excessive levels of proinflammatory cytokines and widespread tissue damage. Recent studies have painted a more complex picture of cytokine networks and their contributions to clinical outcomes. While many cytokines clearly inflict immunopathology, others have non-pathological delimited roles in sending alarm signals, facilitating viral clearance, and promoting tissue repair, such as the IL-33-amphiregulin axis, which plays a key role in resolving some types of lung damage. Recent literature suggests that type 2 cytokines, traditionally thought of as not involved in anti-influenza immunity, may play an important regulatory role. Here, we discuss the diverse roles played by cytokines after influenza infection and highlight new, serene features of the cytokine storm, while highlighting the specific functions of relevant cytokines that perform unique immune functions and may have applications for influenza therapy.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 48 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 12 25%
Student > Ph. D. Student 9 19%
Researcher 7 15%
Student > Bachelor 7 15%
Student > Master 5 10%
Other 8 17%
Readers by discipline Count As %
Unspecified 15 31%
Agricultural and Biological Sciences 9 19%
Immunology and Microbiology 8 17%
Biochemistry, Genetics and Molecular Biology 6 13%
Medicine and Dentistry 5 10%
Other 5 10%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 April 2019.
All research outputs
#6,799,342
of 13,375,725 outputs
Outputs from Seminars in Immunopathology
#152
of 340 outputs
Outputs of similar age
#101,454
of 267,755 outputs
Outputs of similar age from Seminars in Immunopathology
#4
of 15 outputs
Altmetric has tracked 13,375,725 research outputs across all sources so far. This one is in the 48th percentile – i.e., 48% of other outputs scored the same or lower than it.
So far Altmetric has tracked 340 research outputs from this source. They receive a mean Attention Score of 3.3. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 267,755 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.