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The previous use of digoxin does not worsen early outcome of acute coronary syndromes: an analysis of the ARIAM Registry

Overview of attention for article published in Internal and Emergency Medicine, December 2013
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17 Mendeley
Title
The previous use of digoxin does not worsen early outcome of acute coronary syndromes: an analysis of the ARIAM Registry
Published in
Internal and Emergency Medicine, December 2013
DOI 10.1007/s11739-013-1032-9
Pubmed ID
Authors

Juan Carlos Garcia-Rubira, Manuel Calvo-Taracido, Francisca Francisco-Aparicio, Manuel Almendro-Delia, Alejandro Recio-Mayoral, Antonio Reina Toral, Oscar Aramburu-Bodas, Pastora Gallego García de Vinuesa, José Maria Cruz Fernández, Angel Garcia Alcántara, Rafael Hidalgo-Urbano

Abstract

The aim of the study was to determine the influence of the previous use of digoxin on the hospital mortality and complications of patients admitted because of acute coronary syndrome (ACS). We analyzed the data of patients included in the ARIAM-Andalucia Registry, which involves 49 hospitals in Andalucia, Spain, from 2007 to 2012. Patients on digoxin treatment prior to their admission because of ACS constituted the digoxin group (DG), and were compared with the group of patients not on digoxin. Logistic regression and propensity score matching were used to analyze the differences. We included 20,331 patients, of whom 244 (1.2 %) were on digoxin. DG patients were older (73.1 vs 63.7 years old), more often women, and had more diabetes, hypertension, previous myocardial infarction, heart failure, stroke, atrial fibrillation, peripheral vascular disease, obstructive pulmonary disease or kidney disease. On univariate analysis, DG patients had significantly higher hospital mortality (13.5 vs 5.3 % P < 0.001), and more cardiogenic shock, but less ventricular fibrillation, and no differences in atrioventricular block, stroke or reinfarction. After the multivariate analysis, DG had no significant influence on hospital prognosis [odds ratio (OR) 1.21, 95 % confidence interval 0.79-1.86]. The analysis of a propensity-matched cohort of 464 patients (232 DG and 232 NoDG) did not find differences in hospital mortality (13.4 vs 13.4 %) nor other complications. In our cohort of ACS patients, the previous treatment with digoxin was not associated with an increase in dysrhythmic complications nor was an independent predictor of mortality during hospitalization.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 6%
Netherlands 1 6%
Unknown 15 88%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 24%
Unspecified 3 18%
Student > Master 3 18%
Student > Postgraduate 1 6%
Other 1 6%
Other 5 29%
Readers by discipline Count As %
Medicine and Dentistry 7 41%
Unspecified 6 35%
Mathematics 1 6%
Computer Science 1 6%
Agricultural and Biological Sciences 1 6%
Other 1 6%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 January 2014.
All research outputs
#7,888,219
of 12,572,270 outputs
Outputs from Internal and Emergency Medicine
#202
of 387 outputs
Outputs of similar age
#122,722
of 239,728 outputs
Outputs of similar age from Internal and Emergency Medicine
#6
of 9 outputs
Altmetric has tracked 12,572,270 research outputs across all sources so far. This one is in the 23rd percentile – i.e., 23% of other outputs scored the same or lower than it.
So far Altmetric has tracked 387 research outputs from this source. They receive a mean Attention Score of 4.6. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
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