@subversivepsych The immune response to viral activity (eg. VZV, EBV, etc.) results in tryptophan being diverted to the kynurenine pathway; kynurenine can cross the BBB; kynurenic acid can lower dopamine (used to make noradrenaline) affecting concentration
Changes in serum levels of kynurenine metabolites in paediatric patients affected by ADHD https://t.co/7iQ3ppItvR "children with ADHD showed a reduction in serum levels of anthranilic acid (−60%), kynurenic acid (−11.2%), and xanthurenic acid (−12.5%)."
Changes in serum levels of kynurenine metabolites in paediatric patients affected by ADHD. https://t.co/U9q8jdpmp0 “serum levels of tryptophan (+11.0%) and kynurenine (+48.6%) were significantly enhanced, and levels of quinolinic acid were unchanged in c
アントラニル酸濃度が低い、トリプトファン濃度が高いとADHDである可能性が高い。Changes in serum levels of kynurenine metabolites in paediatric patients… https://t.co/EpcnV361hl