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Physiology and cell biology of acupuncture observed in calcium signaling activated by acoustic shear wave

Overview of attention for article published in Pflugers Archiv European Journal of Physiology, July 2011
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#14 of 1,233)
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

blogs
2 blogs
twitter
5 tweeters

Citations

dimensions_citation
18 Dimensions

Readers on

mendeley
48 Mendeley
Title
Physiology and cell biology of acupuncture observed in calcium signaling activated by acoustic shear wave
Published in
Pflugers Archiv European Journal of Physiology, July 2011
DOI 10.1007/s00424-011-0993-7
Pubmed ID
Authors

Geng Li, Jie-Ming Liang, Pei-Wen Li, Xiaoqiang Yao, Peter Zhong Pei, Wei Li, Qi-Hua He, Xifei Yang, Queenie C. C. Chan, Paul Y. S. Cheung, Qi Yuan Ma, Siu Kam Lam, Patrick Y. C. Cheng, Edward S. Yang

Abstract

This article presents a novel model of acupuncture physiology based on cellular calcium activation by an acoustic shear wave (ASW) generated by the mechanical movement of the needle. An acupuncture needle was driven by a piezoelectric transducer at 100 Hz or below, and the ASW in human calf was imaged by magnetic resonance elastography. At the cell level, the ASW activated intracellular Ca(2+) transients and oscillations in fibroblasts and endothelial, ventricular myocytes and neuronal PC-12 cells along with frequency-amplitude tuning and memory capabilities. Monitoring in vivo mammalian experiments with ASW, enhancement of endorphin in blood plasma and blocking by Gd(3+) were observed; and increased Ca(2+) fluorescence in mouse hind leg muscle was imaged by two-photon microscopy. In contrast with traditional acupuncture models, the signal source is derived from the total acoustic energy. ASW signaling makes use of the anisotropy of elasticity of tissues as its waveguides for transmission and that cell activation is not based on the nervous system.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 4%
Brazil 1 2%
Taiwan 1 2%
United States 1 2%
Unknown 43 90%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 29%
Student > Master 10 21%
Researcher 9 19%
Unspecified 3 6%
Other 3 6%
Other 9 19%
Readers by discipline Count As %
Medicine and Dentistry 26 54%
Unspecified 7 15%
Agricultural and Biological Sciences 5 10%
Computer Science 2 4%
Nursing and Health Professions 2 4%
Other 6 13%

Attention Score in Context

This research output has an Altmetric Attention Score of 24. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 November 2018.
All research outputs
#624,486
of 12,974,522 outputs
Outputs from Pflugers Archiv European Journal of Physiology
#14
of 1,233 outputs
Outputs of similar age
#3,892
of 85,031 outputs
Outputs of similar age from Pflugers Archiv European Journal of Physiology
#1
of 10 outputs
Altmetric has tracked 12,974,522 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,233 research outputs from this source. They receive a mean Attention Score of 3.5. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 85,031 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them