| Title |
Evaluation of culture media for the production of secondary metabolites in a natural products screening program
|
|---|---|
| Published in |
AMB Express, December 2013
|
| DOI | 10.1186/2191-0855-3-71 |
| Pubmed ID | |
| Authors |
Karen M VanderMolen, Huzefa A Raja, Tamam El-Elimat, Nicholas H Oberlies |
| Abstract |
Variation in the growing environment can have significant impacts on the quantity and diversity of fungal secondary metabolites. In the industrial setting, optimization of growing conditions can lead to significantly increased production of a compound of interest. Such optimization becomes challenging in a drug-discovery screening situation, as the ideal conditions for one organism may induce poor metabolic diversity for a different organism. Here, the impact of different media types, including six liquid media and five solid media, on the secondary metabolite production of three fungal strains was examined in the context of the drug-discovery screening process. The relative production of marker compounds was used to evaluate the usefulness and reliability of each medium for the purpose of producing secondary metabolites. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 330 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Indonesia | 1 | <1% |
| India | 1 | <1% |
| Ireland | 1 | <1% |
| Unknown | 327 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 55 | 17% |
| Student > Master | 54 | 16% |
| Student > Bachelor | 54 | 16% |
| Researcher | 31 | 9% |
| Student > Doctoral Student | 18 | 5% |
| Other | 39 | 12% |
| Unknown | 79 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 78 | 24% |
| Biochemistry, Genetics and Molecular Biology | 58 | 18% |
| Chemistry | 41 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 23 | 7% |
| Immunology and Microbiology | 21 | 6% |
| Other | 21 | 6% |
| Unknown | 88 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 December 2013.
All research outputs
#20,213,623
of 22,736,112 outputs
Outputs from AMB Express
#965
of 1,229 outputs
Outputs of similar age
#248,172
of 286,036 outputs
Outputs of similar age from AMB Express
#3
of 9 outputs
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So far Altmetric has tracked 1,229 research outputs from this source. They receive a mean Attention Score of 2.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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