Title |
Biomarkers in autism spectrum disorder: the old and the new
|
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Published in |
Psychopharmacology, October 2013
|
DOI | 10.1007/s00213-013-3290-7 |
Pubmed ID | |
Authors |
Barbara Ruggeri, Ugis Sarkans, Gunter Schumann, Antonio M. Persico |
Abstract |
Autism spectrum disorder (ASD) is a complex heterogeneous neurodevelopmental disorder with onset during early childhood and typically a life-long course. The majority of ASD cases stems from complex, 'multiple-hit', oligogenic/polygenic underpinnings involving several loci and possibly gene-environment interactions. These multiple layers of complexity spur interest into the identification of biomarkers able to define biologically homogeneous subgroups, predict autism risk prior to the onset of behavioural abnormalities, aid early diagnoses, predict the developmental trajectory of ASD children, predict response to treatment and identify children at risk for severe adverse reactions to psychoactive drugs. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | <1% |
Argentina | 1 | <1% |
United Kingdom | 1 | <1% |
Spain | 1 | <1% |
Korea, Republic of | 1 | <1% |
Unknown | 347 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 57 | 16% |
Student > Master | 49 | 14% |
Researcher | 43 | 12% |
Student > Bachelor | 40 | 11% |
Student > Postgraduate | 23 | 7% |
Other | 57 | 16% |
Unknown | 84 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 54 | 15% |
Medicine and Dentistry | 39 | 11% |
Agricultural and Biological Sciences | 35 | 10% |
Neuroscience | 26 | 7% |
Biochemistry, Genetics and Molecular Biology | 21 | 6% |
Other | 71 | 20% |
Unknown | 107 | 30% |