Title |
A Review of Emergency Cardiopulmonary Bypass for Severe Poisoning by Cardiotoxic Drugs
|
---|---|
Published in |
Journal of Medical Toxicology, December 2012
|
DOI | 10.1007/s13181-012-0281-8 |
Pubmed ID | |
Authors |
Nicholas J. Johnson, David F. Gaieski, Steven R. Allen, Jeanmarie Perrone, Francis DeRoos |
Abstract |
Cardiovascular collapse remains a leading cause of death in severe acute drug intoxication. Commonly prescribed medications such as antidysrhythmics, calcium channel antagonists, and beta adrenergic receptor antagonists can cause refractory cardiovascular collapse in massive overdose. Emergency cardiopulmonary bypass (ECPB), a modality originating in cardiac surgery, is a rescue technique that has been successfully implemented in the treatment of refractory cardiogenic shock and cardiac arrest unresponsive to traditional medical interventions. More recently a growing number of animal studies, case reports, and case series have documented its use in refractory hemodynamic collapse in poisoned patients. This article will review current ECPB techniques and explore its growing role in the treatment of severely hemodynamically compromised poisoned patients. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 8 | 23% |
Australia | 3 | 9% |
Italy | 2 | 6% |
Canada | 2 | 6% |
United Arab Emirates | 1 | 3% |
Turkey | 1 | 3% |
Colombia | 1 | 3% |
New Zealand | 1 | 3% |
Curaçao | 1 | 3% |
Other | 1 | 3% |
Unknown | 14 | 40% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 22 | 63% |
Practitioners (doctors, other healthcare professionals) | 9 | 26% |
Scientists | 3 | 9% |
Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 3% |
Unknown | 56 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 13 | 22% |
Student > Doctoral Student | 12 | 21% |
Researcher | 6 | 10% |
Student > Postgraduate | 6 | 10% |
Professor > Associate Professor | 4 | 7% |
Other | 14 | 24% |
Unknown | 3 | 5% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 44 | 76% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
Nursing and Health Professions | 2 | 3% |
Environmental Science | 1 | 2% |
Biochemistry, Genetics and Molecular Biology | 1 | 2% |
Other | 4 | 7% |
Unknown | 4 | 7% |