The Porirua Protocol in the Treatment of Clozapine-Induced Gastrointestinal Hypomotility and Constipation: A Pre- and Post-Treatment Study

Overview of attention for article published in CNS Drugs, November 2016

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@woodford_henry @dr_shibley The Porirua Protocol: Guidance to prevent clozapine-related constipation. Clozapine induces constipation by reducing gut motility. But original study did only compare no laxatives to docusate and Senna https://t.co/fiDxdSu7Uc

01 Sep 2021

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Docusate, senna & macrogol reduces colon transit time in #clozapine constipation. Severe GI #hypomotility: 64 to 21% https://t.co/lPLcuI7isx

02 Sep 2017

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