| Title |
The association of glycogen synthase kinase-3beta (GSK-3β) gene polymorphism with kidney function in long-term lithium-treated bipolar patients
|
|---|---|
| Published in |
International Journal of Bipolar Disorders, June 2013
|
| DOI | 10.1186/2194-7511-1-8 |
| Pubmed ID | |
| Authors |
Janusz K Rybakowski, Maria Abramowicz, Aleksandra Szczepankiewicz, Michal Michalak, Joanna Hauser, Stanislaw Czekalski |
| Abstract |
Most bipolar patients experience a reduction in urinary concentrating ability within a few weeks of starting lithium treatment. This phenomenon may be connected with the effect of lithium on the glycogen synthase kinase-3beta (GSK-3β) present in the renal tubules. The GSK-3β gene is located on chromosome 3q13 and possesses a functional -50 C/T polymorphism. In the present study, we estimated this polymorphism in a group of long-term lithium-treated patients and assessed its association with various parameters of kidney function, including novel markers of kidney injury such as serum neutrophil gelatinase-associated lipocalin (NGAL) and urinary beta2-microglobulin (β2-MG). |
Mendeley readers
The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 11 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 2 | 18% |
| Student > Bachelor | 2 | 18% |
| Unspecified | 1 | 9% |
| Student > Ph. D. Student | 1 | 9% |
| Professor > Associate Professor | 1 | 9% |
| Other | 1 | 9% |
| Unknown | 3 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 5 | 45% |
| Unspecified | 1 | 9% |
| Neuroscience | 1 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 9% |
| Unknown | 3 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 June 2013.
All research outputs
#20,195,024
of 22,712,476 outputs
Outputs from International Journal of Bipolar Disorders
#256
of 282 outputs
Outputs of similar age
#172,216
of 196,704 outputs
Outputs of similar age from International Journal of Bipolar Disorders
#5
of 5 outputs
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