https://t.co/djStAFKl6S "Studies have demonstrated that physiological reconstitution of zinc restrains immune activation, whereas zinc deficiency, in the setting of severe infection, provokes a systemic increase in NF-κB activation."
https://t.co/djStAFKl6S "Zinc can exchange redox active metals, such as copper and iron, in certain binding sites and attenuate cellular site-specific oxidative injury."
https://t.co/djStAFKl6S "On the other hand, zinc exerts its antioxidant effect via two acute mechanisms, one of which is the stabilization of protein sulfhydryls against oxidation." "The second mechanism consists in antagonizing transition metal-catalyze
https://t.co/djStAFKl6S "Furthermore, zinc increases the activation of antioxidant proteins and enzymes, such as glutathione and catalase."
https://t.co/djStAFKl6S "These metal-binding cysteine-rich proteins are responsible for maintaining zinc-related cell homeostasis and act as potent electrophilic scavengers and cytoprotective agents."
https://t.co/djStAFKl6S "The mineral modulates immune response and exhibits antioxidant and anti-inflammatory activity." "Zinc retards oxidative processes on a long-term basis by inducing the expression of metallothioneins."
Antioxidant and anti-inflammatory effects of zinc. Zinc-dependent NF-κB signaling https://t.co/djStAFKl6S
RT @PaulPaul49: https://t.co/3hY8MotpZR The major intracellular sites of ROS production in eukaryotic cells are mitochondrial electron tra…
Antioxidant and anti-inflammatory effects of zinc. Zinc-dependent NF-κB signaling https://t.co/dIm8rzlBRv
RT @PaulPaul49: https://t.co/3hY8MotpZR The element is essential to the structure and function of about 2800 macromolecules and over 300 en…
RT @Dharmen46587056: Antioxidant and anti-inflammatory effects of zinc https://t.co/4tes5W9DBw
https://t.co/3hY8MotpZR impaired zinc homeostasis, constantly increased proinflammatory cytokines oxidative stress feature prominently in multiple chronic diseases zinc supplementation adjusted to the actual requirement may prove to be a useful preventive
https://t.co/3hY8MotpZR demonstrated for the first time that zinc supplementation prevents abdominal aortic aneurysm (AAA) formation in rats by induction of A20-mediated inhibition of the NF-κB canonical signaling pathway.
https://t.co/3hY8MotpZR In terms of adaptive immunity, zinc deficiency is responsible for thymic atrophy and subsequent T-cell lymphopenia as well as reduction of B cells, affecting antibody production. Zinc is also crucial for the balance between the di
https://t.co/3hY8MotpZR The effect of zinc on innate and adaptive immunity is undisputable. Zinc is critical for maintaining membrane barrier structure and function. Its deficiency causes damage to epidermal cells and to the linings of the gastrointestina
https://t.co/3hY8MotpZR The critical transcription factor that regulates the expression of genes encoding above mentioned antioxidant and detoxifying molecules (GSH, SOD, GST, HO-1), nuclear factor erythroid 2-related factor 2 (Nrf2), has been proven to be
https://t.co/3hY8MotpZR The major intracellular sites of ROS production in eukaryotic cells are mitochondrial electron transport chain, peroxisomal long-chain fatty acid oxidation, and respiratory burst mainly via activation of NADPH oxidases. In addition
https://t.co/3hY8MotpZR @merogenomics
https://t.co/3hY8MotpZR The element is essential to the structure and function of about 2800 macromolecules and over 300 enzymes. It is a component of about 10% of human proteins including transcription factors and key enzymes regulating cellular processes
Zinc an antioxidatn & antiinflammtory agent. Essential nutrient for skin & hair growth !!! https://t.co/9UB0CT15hg