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Presynaptic neuromuscular transmission defect in the stiff person syndrome

Overview of attention for article published in BMC Neurology, December 2016
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Title
Presynaptic neuromuscular transmission defect in the stiff person syndrome
Published in
BMC Neurology, December 2016
DOI 10.1186/s12883-016-0773-2
Pubmed ID
Authors

Y. L. Lo, Y. E. Tan

Abstract

The stiff person syndrome (SPS) is a rare disorder characterized by muscular rigidity and stiffness. We describe an SPS patient presenting with longstanding fatigue and electrophysiological evidence of presynaptic neuromuscular transmission defect, who responded to administration of pyridostigmine. In contrast, no electrophysiolgical evidence of neuromuscular transmission defect was demonstrated in 2 other SPS patients without fatigue symptoms. Our findings suggest that glutamic acid decarboxylase (GAD) antibodies may play a role in presynaptic neuromuscular transmission defect of SPS patients with fatigue.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Other 4 18%
Professor 2 9%
Student > Ph. D. Student 2 9%
Librarian 1 5%
Student > Master 1 5%
Other 2 9%
Unknown 10 45%
Readers by discipline Count As %
Neuroscience 3 14%
Nursing and Health Professions 2 9%
Medicine and Dentistry 2 9%
Arts and Humanities 1 5%
Agricultural and Biological Sciences 1 5%
Other 0 0%
Unknown 13 59%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 January 2017.
All research outputs
#20,382,391
of 22,931,367 outputs
Outputs from BMC Neurology
#2,156
of 2,453 outputs
Outputs of similar age
#350,696
of 416,732 outputs
Outputs of similar age from BMC Neurology
#38
of 42 outputs
Altmetric has tracked 22,931,367 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,453 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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