@ejustin46 Cholinergic neurons are most susceptible to #MitochondrialDysfunction & neurodegenerative influences — because acetylcholine synthesis is in competition for acetyl-CoA with mitochondrial energy metabolism. What about other mechanisms of dop
RT @8Eevert: @moosiemacgiolla @Canal1point5 #neurodegenerative states suppress acetyl-CoA metabolism and induce #cholinergic deficits > ce…
@agingdoc1 Interesting that fatty acid oxidation in astrocytes is recently reported, yet elsewhere view prevails that “pyruvate through PDHC reaction is almost exclusive source of acetyl-CoA in neurons and other types of brain cells”. https://t.co/NA6tZb0M
RT @8Eevert: @moosiemacgiolla @Canal1point5 #neurodegenerative states suppress acetyl-CoA metabolism and induce #cholinergic deficits > ce…
RT @8Eevert: @moosiemacgiolla @Canal1point5 #neurodegenerative states suppress acetyl-CoA metabolism and induce #cholinergic deficits > ce…
@moosiemacgiolla @Canal1point5 #neurodegenerative states suppress acetyl-CoA metabolism and induce #cholinergic deficits > cells utilize acetyl-CoA for energy production in mitochondria > cholinergic neurons require additional acetyl-CoA for #acetyl
@KevinJTraceyMD @nytimes @cdcaron “try to maintain high vagus nerve activity through mindfulness, exercise and paced breathing,” Dr. Tracey said.” And stop the all-too-convenient ‘sugar abuse’ of cholinergic 🧠/CNS that is wrecking individuals and society
@WesElyMD @dianaberrent @Paul_Wischmeyer @CIBScenter Mitochondria being the site of acetyl-CoA production. https://t.co/NA6tZaJaJi Cholinergic Anti-Inflammatory Pathway
@sadneurons Acetyl-CoA the Key Factor for Survival or Death of Cholinergic Neurons in Course of Neurodegenerat... http://t.co/H1MKO5jcmf