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Synapsable quadruplex-mediated fibers

Overview of attention for article published in Nanoscale Research Letters, May 2013
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Synapsable quadruplex-mediated fibers
Published in
Nanoscale Research Letters, May 2013
DOI 10.1186/1556-276x-8-210
Pubmed ID

Miguel Angel Mendez, Veronika A Szalai


We have fabricated a DNA-based nanofiber created by self-assembly of guanine quadruplex (Hoogsteen base pairing) and double-stranded DNA (Watson-Crick base pairing). When duplexes containing a long stretch of contiguous guanines and single-stranded overhangs are incubated in potassium-containing buffer, the preformed duplexes create high molecular weight species that contain quadruplexes. In addition to observation of these larger species by gel electrophoresis, solutions were analyzed by atomic force microscopy to reveal nanofibers. Analysis of the atomic force microscopy images indicates that fibers form with lengths ranging from 250 to 2,000 nm and heights from 0.45 to 4.0 nm. This work is a first step toward the creation of new structurally heterogeneous (quadruplex/duplex), yet controllable, DNA-based materials exhibiting novel properties suitable for a diverse array of nanotechnology applications.

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 5%
Unknown 18 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 42%
Researcher 2 11%
Student > Doctoral Student 1 5%
Student > Bachelor 1 5%
Student > Master 1 5%
Other 3 16%
Unknown 3 16%
Readers by discipline Count As %
Chemistry 8 42%
Agricultural and Biological Sciences 4 21%
Physics and Astronomy 1 5%
Biochemistry, Genetics and Molecular Biology 1 5%
Medicine and Dentistry 1 5%
Other 1 5%
Unknown 3 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 May 2013.
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So far Altmetric has tracked 380 research outputs from this source. They receive a mean Attention Score of 0.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 84,930 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.