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Synapsable quadruplex-mediated fibers

Overview of attention for article published in Nanoscale Research Letters, May 2013
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Title
Synapsable quadruplex-mediated fibers
Published in
Nanoscale Research Letters, May 2013
DOI 10.1186/1556-276x-8-210
Pubmed ID
Authors

Miguel Angel Mendez, Veronika A Szalai

Abstract

We have fabricated a DNA-based nanofiber created by self-assembly of guanine quadruplex (Hoogsteen base pairing) and double-stranded DNA (Watson-Crick base pairing). When duplexes containing a long stretch of contiguous guanines and single-stranded overhangs are incubated in potassium-containing buffer, the preformed duplexes create high molecular weight species that contain quadruplexes. In addition to observation of these larger species by gel electrophoresis, solutions were analyzed by atomic force microscopy to reveal nanofibers. Analysis of the atomic force microscopy images indicates that fibers form with lengths ranging from 250 to 2,000 nm and heights from 0.45 to 4.0 nm. This work is a first step toward the creation of new structurally heterogeneous (quadruplex/duplex), yet controllable, DNA-based materials exhibiting novel properties suitable for a diverse array of nanotechnology applications.

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 6%
Unknown 16 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 41%
Researcher 2 12%
Other 1 6%
Student > Bachelor 1 6%
Student > Master 1 6%
Other 3 18%
Unknown 2 12%
Readers by discipline Count As %
Chemistry 8 47%
Agricultural and Biological Sciences 3 18%
Physics and Astronomy 1 6%
Medicine and Dentistry 1 6%
Biochemistry, Genetics and Molecular Biology 1 6%
Other 1 6%
Unknown 2 12%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 May 2013.
All research outputs
#2,902,882
of 3,628,651 outputs
Outputs from Nanoscale Research Letters
#89
of 380 outputs
Outputs of similar age
#66,250
of 84,930 outputs
Outputs of similar age from Nanoscale Research Letters
#2
of 3 outputs
Altmetric has tracked 3,628,651 research outputs across all sources so far. This one is in the 2nd percentile – i.e., 2% of other outputs scored the same or lower than it.
So far Altmetric has tracked 380 research outputs from this source. They receive a mean Attention Score of 0.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.