Title |
General anesthesia with remimazolam for a pediatric patient with MELAS and recurrent epilepsy: a case report
|
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Published in |
JA Clinical Reports, September 2022
|
DOI | 10.1186/s40981-022-00564-x |
Pubmed ID | |
Authors |
Yusuke Yamadori, Yuki Yamagami, Yukihisa Matsumoto, Mari Koizumi, Akiyo Nakamura, Daiskuke Mizuta, Kyoko Yasuda, Gotaro Shirakami |
Abstract |
Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) is a mitochondrial disease. We report here the safe use of remimazolam in a pediatric MELAS patient. A 10-year-old girl (118 cm, 16 kg) was scheduled for an open gastrostomy to improve nutrition and epileptic seizure control. We induced and maintained general anesthesia with remimazolam, remifentanil, fentanyl, and rocuronium. We also performed a bilateral subcostal transversus abdominis plane block before the surgery. The surgery finished uneventfully. After we discontinued remimazolam administration, the patient woke up immediately but calmly without flumazenil. Epileptic seizures did not occur during intra- and early post-operative periods. Remimazolam enabled us to provide a pediatric MELAS patient with general anesthesia without causing delayed emergence or epileptic seizures. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Science communicators (journalists, bloggers, editors) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 12 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 1 | 8% |
Professor | 1 | 8% |
Lecturer | 1 | 8% |
Student > Doctoral Student | 1 | 8% |
Student > Master | 1 | 8% |
Other | 0 | 0% |
Unknown | 7 | 58% |
Readers by discipline | Count | As % |
---|---|---|
Nursing and Health Professions | 2 | 17% |
Medicine and Dentistry | 2 | 17% |
Psychology | 1 | 8% |
Unknown | 7 | 58% |