Mainstay of Rx for AIDS-related KS (like this case) is combination antiretroviral therapy (CART). CART —> HIV suppression—> CD4 recovery —> HHV8 suppression —> decrease in KS tumor burden Caution: IRIS immune reconstitution inflammatory synd
In 1996, HHV-8 was discovered as the infectious agent causing Kaposi’s sarcoma. At that time, it was called Kaposi’s sarcoma-associated herpesvirus, now known as human herpesvirus-8. https://t.co/HPdDOE3qge
Types of Kaposi’s sarcoma 1. Classic (older Mediterranean men) 2. Endemic (equatorial Africa) 3. AIDS-KS (like this case - check HIV CD4 as you suggested) 4. Iatrogenic (transplant patients / those on immunosuppressive drugs) 10.1007/s13555-016-0152-3 h
An update on Kaposi’s sarcoma from doctors @NYULMC https://t.co/5mAMNXwLiP #AIDS #HIV https://t.co/FhnRI5mvw4