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Effects of Exercise Training on Chronic Inflammation in Obesity

Overview of attention for article published in Sports Medicine, March 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)

Mentioned by

17 tweeters
1 Facebook page


87 Dimensions

Readers on

144 Mendeley
Effects of Exercise Training on Chronic Inflammation in Obesity
Published in
Sports Medicine, March 2013
DOI 10.1007/s40279-013-0023-3
Pubmed ID

Tongjian You, Nicole C. Arsenis, Beth L. Disanzo, Michael J. LaMonte


Chronic, systemic inflammation is an independent risk factor for several major clinical diseases. In obesity, circulating levels of inflammatory markers are elevated, possibly due to increased production of pro-inflammatory cytokines from several tissues/cells, including macrophages within adipose tissue, vascular endothelial cells and peripheral blood mononuclear cells. Recent evidence supports that adipose tissue hypoxia may be an important mechanism through which enlarged adipose tissue elicits local tissue inflammation and further contributes to systemic inflammation. Current evidence supports that exercise training, such as aerobic and resistance exercise, reduces chronic inflammation, especially in obese individuals with high levels of inflammatory biomarkers undergoing a longer-term intervention. Several studies have reported that this effect is independent of the exercise-induced weight loss. There are several mechanisms through which exercise training reduces chronic inflammation, including its effect on muscle tissue to generate muscle-derived, anti-inflammatory 'myokine', its effect on adipose tissue to improve hypoxia and reduce local adipose tissue inflammation, its effect on endothelial cells to reduce leukocyte adhesion and cytokine production systemically, and its effect on the immune system to lower the number of pro-inflammatory cells and reduce pro-inflammatory cytokine production per cell. Of these potential mechanisms, the effect of exercise training on adipose tissue oxygenation is worth further investigation, as it is very likely that exercise training stimulates adipose tissue angiogenesis and increases blood flow, thereby reducing hypoxia and the associated chronic inflammation in adipose tissue of obese individuals.

Twitter Demographics

The data shown below were collected from the profiles of 17 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 144 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
Canada 1 <1%
Unknown 142 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 37 26%
Student > Ph. D. Student 27 19%
Student > Bachelor 19 13%
Unspecified 18 13%
Researcher 13 9%
Other 30 21%
Readers by discipline Count As %
Sports and Recreations 33 23%
Unspecified 27 19%
Medicine and Dentistry 27 19%
Biochemistry, Genetics and Molecular Biology 16 11%
Agricultural and Biological Sciences 15 10%
Other 26 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 February 2017.
All research outputs
of 13,433,327 outputs
Outputs from Sports Medicine
of 2,187 outputs
Outputs of similar age
of 147,137 outputs
Outputs of similar age from Sports Medicine
of 15 outputs
Altmetric has tracked 13,433,327 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,187 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 31.9. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 147,137 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.