Title |
Impact of inactivity and exercise on the vasculature in humans
|
---|---|
Published in |
European Journal of Applied Physiology, November 2009
|
DOI | 10.1007/s00421-009-1260-x |
Pubmed ID | |
Authors |
Dick H. J. Thijssen, Andrew J. Maiorana, Gerry O’Driscoll, Nigel T. Cable, Maria T. E. Hopman, Daniel J. Green |
Abstract |
The effects of inactivity and exercise training on established and novel cardiovascular risk factors are relatively modest and do not account for the impact of inactivity and exercise on vascular risk. We examine evidence that inactivity and exercise have direct effects on both vasculature function and structure in humans. Physical deconditioning is associated with enhanced vasoconstrictor tone and has profound and rapid effects on arterial remodelling in both large and smaller arteries. Evidence for an effect of deconditioning on vasodilator function is less consistent. Studies of the impact of exercise training suggest that both functional and structural remodelling adaptations occur and that the magnitude and time-course of these changes depends upon training duration and intensity and the vessel beds involved. Inactivity and exercise have direct "vascular deconditioning and conditioning" effects which likely modify cardiovascular risk. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 5 | 45% |
Australia | 2 | 18% |
Slovenia | 1 | 9% |
United States | 1 | 9% |
Germany | 1 | 9% |
Unknown | 1 | 9% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 6 | 55% |
Scientists | 5 | 45% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 6 | 2% |
Brazil | 2 | <1% |
France | 2 | <1% |
Spain | 2 | <1% |
United Kingdom | 2 | <1% |
Australia | 1 | <1% |
South Africa | 1 | <1% |
Denmark | 1 | <1% |
United States | 1 | <1% |
Other | 0 | 0% |
Unknown | 362 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 69 | 18% |
Student > Ph. D. Student | 65 | 17% |
Student > Bachelor | 55 | 14% |
Researcher | 43 | 11% |
Student > Doctoral Student | 28 | 7% |
Other | 58 | 15% |
Unknown | 62 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 104 | 27% |
Sports and Recreations | 87 | 23% |
Agricultural and Biological Sciences | 36 | 9% |
Nursing and Health Professions | 23 | 6% |
Social Sciences | 13 | 3% |
Other | 42 | 11% |
Unknown | 75 | 20% |