Title |
Therapeutic plasma exchange in heart transplantation: role of coagulation assessment with thromboelastometry
|
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Published in |
JA Clinical Reports, October 2016
|
DOI | 10.1186/s40981-016-0058-1 |
Pubmed ID | |
Authors |
Andrew Crabbe, John S. McNeil, Seema P. Deshpande, Zachary Kon, Si M. Pham, Kenichi A. Tanaka |
Abstract |
Therapeutic plasma exchange (TPE) is a potentially life-saving procedure which effectively removes donor-specific human leukocyte antigen (HLA) antibodies from the bloodstream, allowing critically ill heart transplant recipients to receive a donor organ with less wait time, and reducing the risk of acute organ rejection. The bulk of coagulation factors is initially removed from the blood during TPE using albumin and is later replaced with allogeneic plasma. Coagulopathy may develop during TPE and then can persist due to intraoperative blood loss and hemodilution during surgery and cardiopulmonary bypass. We hereby describe the utility of rotational thromboelastometry to assess rapid coagulation changes during TPE and subsequent heart transplant (HT) surgery. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Australia | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 18 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 3 | 17% |
Professor > Associate Professor | 3 | 17% |
Student > Master | 3 | 17% |
Librarian | 2 | 11% |
Other | 2 | 11% |
Other | 3 | 17% |
Unknown | 2 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 9 | 50% |
Biochemistry, Genetics and Molecular Biology | 2 | 11% |
Arts and Humanities | 2 | 11% |
Immunology and Microbiology | 1 | 6% |
Engineering | 1 | 6% |
Other | 0 | 0% |
Unknown | 3 | 17% |