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A glow of HLA typing in organ transplantation

Overview of attention for article published in Clinical and Translational Medicine, February 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (73rd percentile)

Mentioned by

twitter
1 tweeter
facebook
1 Facebook page
wikipedia
1 Wikipedia page

Citations

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30 Dimensions

Readers on

mendeley
169 Mendeley
Title
A glow of HLA typing in organ transplantation
Published in
Clinical and Translational Medicine, February 2013
DOI 10.1186/2001-1326-2-6
Pubmed ID
Authors

Batool Mutar Mahdi

Abstract

The transplant of organs and tissues is one of the greatest curative achievements of this century. In organ transplantation, the adaptive immunity is considered the main response exerted to the transplanted tissue, since the main goal of the immune response is the MHC (major histocompatibility complex) molecules expressed on the surface of donor cells. Cell surface molecules that induce an antigenic stimulus cause the rejection immune response to grafted tissue or organ. A wide variety of transplantation antigens have been described, including the major histocompatibility molecules, minor histocompatibility antigens, ABO blood group antigens and endothelial cell antigens. The sensitization to MHC antigens may be caused by transfusions, pregnancy, or failed previous grafts leading to development of anti-human leukocyte antigen (HLA) antibodies that are important factor responsible for graft rejection in solid organ transplantation and play a role in post-transfusion complication Anti-HLA Abs may be present in healthy individuals. Methods for HLA typing are described, including serological methods, molecular techniques of sequence-specific priming (SSP), sequence-specific oligonucleotide probing (SSOP), Sequence based typing (SBT) and reference strand-based conformation analysis (RSCA) method. Problems with organ transplantation are reservoir of organs and immune suppressive treatments that used to decrease rate of rejection with less side effect and complications.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 169 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
India 1 <1%
Ireland 1 <1%
Australia 1 <1%
Unknown 165 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 36 21%
Student > Master 30 18%
Researcher 27 16%
Student > Ph. D. Student 17 10%
Student > Postgraduate 13 8%
Other 21 12%
Unknown 25 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 46 27%
Biochemistry, Genetics and Molecular Biology 34 20%
Medicine and Dentistry 31 18%
Immunology and Microbiology 14 8%
Nursing and Health Professions 4 2%
Other 15 9%
Unknown 25 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 March 2020.
All research outputs
#4,828,393
of 17,363,630 outputs
Outputs from Clinical and Translational Medicine
#83
of 352 outputs
Outputs of similar age
#41,616
of 157,773 outputs
Outputs of similar age from Clinical and Translational Medicine
#1
of 1 outputs
Altmetric has tracked 17,363,630 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 352 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.6. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 157,773 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them