| Title |
Adolescence as a vulnerable period to alter rodent behavior
|
|---|---|
| Published in |
Cell and Tissue Research, February 2013
|
| DOI | 10.1007/s00441-013-1581-2 |
| Pubmed ID | |
| Authors |
Miriam Schneider |
| Abstract |
Adolescence and puberty are highly important periods for postnatal brain maturation. During adolescence, drastic changes of neuronal architecture and function occur that concomitantly lead to distinct behavioral alterations. Unsurprisingly in view of the multitude of ongoing neurodevelopmental processes in the adolescent brain, most adult neuropsychiatric disorders have their roots exactly during this time span. Adolescence and puberty are therefore crucial developmental periods in terms of understanding the causes and mechanisms of adult mental illness. Valid animal models for adolescent behavior and neurodevelopment might offer better insights into the underlying mechanisms and help to identify specific time windows with heightened susceptibility during development. In order to increase the translational value of such models, we urgently need to define the detailed timing of adolescence and puberty in laboratory rodents. The aim of the present review is to provide a more precise delineation of the time course of these developmental periods during postnatal life in rats and mice and to discuss the impact of adolescence and related neurodevelopmental processes on the heightened susceptibility for mental disorders. |
Mendeley readers
The data shown below were compiled from readership statistics for 212 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | <1% |
| India | 1 | <1% |
| Unknown | 210 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 40 | 19% |
| Student > Bachelor | 28 | 13% |
| Student > Doctoral Student | 22 | 10% |
| Researcher | 18 | 8% |
| Student > Master | 17 | 8% |
| Other | 34 | 16% |
| Unknown | 53 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 58 | 27% |
| Agricultural and Biological Sciences | 32 | 15% |
| Psychology | 25 | 12% |
| Medicine and Dentistry | 11 | 5% |
| Biochemistry, Genetics and Molecular Biology | 10 | 5% |
| Other | 15 | 7% |
| Unknown | 61 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 August 2022.
All research outputs
#8,187,876
of 24,541,341 outputs
Outputs from Cell and Tissue Research
#546
of 2,314 outputs
Outputs of similar age
#66,874
of 196,945 outputs
Outputs of similar age from Cell and Tissue Research
#6
of 36 outputs
Altmetric has tracked 24,541,341 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,314 research outputs from this source. They receive a mean Attention Score of 3.5. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
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