↓ Skip to main content

High Levels of Inflammation and Insulin Resistance in Obstructive Sleep Apnea Patients with Hypertension

Overview of attention for article published in Inflammation, April 2012
Altmetric Badge

Mentioned by

twitter
1 tweeter

Citations

dimensions_citation
12 Dimensions

Readers on

mendeley
18 Mendeley
Title
High Levels of Inflammation and Insulin Resistance in Obstructive Sleep Apnea Patients with Hypertension
Published in
Inflammation, April 2012
DOI 10.1007/s10753-012-9464-3
Pubmed ID
Authors

Xiaoshun Qian, Tong Yin, Tianzhi Li, Chunyan Kang, Ruibiao Guo, Baojun Sun, Changting Liu

Abstract

Hypertension induced by obstructive sleep apnea (OSA) may be multifactorial in origin, and systemic inflammation is one of the major factors. However, OSA patients do not always have the identical probability with hypertension even in patients with the same history and degree of OSA. The aim of this study was to compare the levels of inflammation and insulin resistance in two groups of patients who had the same degree as well as the same long history of OSA, but with/without hypertension. OSA patients (Apnea Hyponea Index, AHI ≥ 40/h, n = 70) were examined by polysomnography and blood analysis for the measurements of fasting plasma glucose, serum insulin (FINS), high-sensitivity C-reactive protein (CRP), peptide C,TNF-α, IL-6, and IL-10. Patients with hypertension (n = 40) had higher level of LDL-C and lower HDL-C levels than patients without hypertension. Almost half (16/40) of OSA patients with hypertension had family history of hypertension. Moreover in OSA patients with hypertension, the levels of TNF-α, IL-6, and CRP were higher, but IL-10 was lower than those without hypertension. FINS, peptide C, HOMA-IR, and HOMA-islet were also higher in OSA patients with hypertension. OSA patients with hypertension have higher level of inflammation and insulin resistance. Systemic inflammation and insulin resistance are both important factors for the development of hypertension in OSA patients.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Finland 1 6%
United States 1 6%
Unknown 16 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 22%
Student > Master 3 17%
Other 3 17%
Student > Bachelor 2 11%
Student > Ph. D. Student 2 11%
Other 4 22%
Readers by discipline Count As %
Medicine and Dentistry 9 50%
Unspecified 2 11%
Agricultural and Biological Sciences 2 11%
Pharmacology, Toxicology and Pharmaceutical Science 1 6%
Immunology and Microbiology 1 6%
Other 3 17%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 January 2013.
All research outputs
#10,936,376
of 12,339,854 outputs
Outputs from Inflammation
#467
of 717 outputs
Outputs of similar age
#238,347
of 282,688 outputs
Outputs of similar age from Inflammation
#8
of 12 outputs
Altmetric has tracked 12,339,854 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 717 research outputs from this source. They receive a mean Attention Score of 2.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 282,688 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.