Title |
Vasculitic emergencies in the intensive care unit: a special focus on cryoglobulinemic vasculitis
|
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Published in |
Annals of Intensive Care, July 2012
|
DOI | 10.1186/2110-5820-2-31 |
Pubmed ID | |
Authors |
Mohamad Zaidan, Eric Mariotte, Lionel Galicier, Bertrand Arnulf, Véronique Meignin, Jérôme Vérine, Alfred Mahr, Élie Azoulay |
Abstract |
Vasculitis is characterized by the infiltration of vessel walls by inflammatory leukocytes with reactive damage and subsequent loss of vessel integrity. The clinical course of systemic vasculitis may be punctuated by acute life-threatening manifestations that require intensive care unit (ICU) admission. Furthermore, the diagnosis may be established in the ICU after admission for a severe inaugural symptom, mostly acute respiratory failure. Among the systemic vasculitides, cryoglobulinemic vasculitis (CV) has been rarely studied in an ICU setting. Severe CV-related complications may involve the kidneys, lungs, heart, gut, and/or central nervous system. The diagnosis of CV in the ICU may be delayed or completely unrecognized. A high level of suspicion is critical to obtain a timely and accurate diagnosis and to initiate appropriate treatment. We describe severe acute manifestations of CV based on six selected patients admitted to our ICU. That all six patients survived suggests the benefit of prompt ICU admission of patients with severe CV. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 33% |
Mexico | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Brazil | 1 | 2% |
Unknown | 44 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 8 | 18% |
Researcher | 8 | 18% |
Professor > Associate Professor | 5 | 11% |
Student > Master | 5 | 11% |
Student > Bachelor | 4 | 9% |
Other | 8 | 18% |
Unknown | 7 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 29 | 64% |
Nursing and Health Professions | 3 | 7% |
Agricultural and Biological Sciences | 2 | 4% |
Decision Sciences | 1 | 2% |
Biochemistry, Genetics and Molecular Biology | 1 | 2% |
Other | 0 | 0% |
Unknown | 9 | 20% |